Loss of TCR responsiveness during thymic education imprints the 'innate' signature on γδ T cells |
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作者姓名: | Sundararajan Jayaraman |
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作者单位: | Department of Surgery, University of Illinois College of Medicine, Peoria, IL, USA |
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摘 要: | T cells expressing γδ determinants are considered innate-like and deviate from the classical αβ T cells in many aspects, including the rapid production of lymphokines following the recognition of 'naked' antigens by the invariant T-cell receptor and failure to differentiate in the periphery.
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关 键 词: | T细胞受体 反应过程 TCR 签名 教育 胸腺 损失 细胞表达 |
收稿时间: | 2014 Jan 22 |
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