乌鲁木齐地区2010年腹泻病原菌耐药性监测与分析

目的 调查2010年乌鲁木齐地区腹泻病原菌耐药性特征,为指导本地区临床合理用药提供参考.方法 对腹泻标本进行细菌学培养,利用生化、血清学方法 对分离菌株进行特异性鉴定.在此基础上,利用K-B纸片扩散法检测病原菌的耐药性.结果 从392份腹泻标本中,分离获得病原菌103株,主要包括47株志贺菌、33株致泻性大肠埃希菌及1...

Surveillance and analysis of antimicrobial resistance of bacterial pathogens isolated from patients with diarrhea in Urumqi in 2010

Objective To investigate antimicrobial resistance of bacterial pathogens isolated from patients with seasonal diar-rhea in Urumqi so as to provide evidence for rational use of drugs.Methods Bacterial pathogens were isolated from fecal speci-mens from diarrheal patients,and identified by biochemical and serological methods.Antimicrobial resistance was tested using K-B diffuse method.Results Totally 103 pathogenic bacteria strains were isolated from 392 samples,mainly including 47 Shigella spp.strains,33 diarrheagenic Escherichia coli strains and 15 Salmonella spp.strains.The isolated strains were generally resistant to am-plicillin with the resistance rate of 75.7%,and to a certain degree resistant to common antimicrobial agents,such as β-lactams,cephalosporins and quinolones.A few isolates were found to be resistant to carbapenems.Conclusions Shigella spp.,diarrheapa-thogenic E.coli and Salmonella spp.are the major pathogens causing the seasonal diarrhea in Urumuqi,and severe antimicrobial re-sistance has been observed.