支架成形术治疗颅外椎动脉硬化狭窄

目的 评价血管内支架成形术治疗颅外椎动脉狭窄的安全性及有效性.方法 回顾性分析2006年4月至2010年3月施行血管内支架成形术治疗的24例颅外椎动脉狭窄病例.MoriA型21例,Mori B型3例.动脉狭窄率60%～95%,平均狭窄率79%±10%.结果 24例共置入球囊扩张式支架24枚.技术成功率100%.术后平均狭窄率下降至4%±6%.随访3～36个月,平均随访22个月.17例有症状病例中,术后15例症状消失.1例治疗部位再狭窄伴短暂性脑缺血发作.1例术前检查提示多发梗死伴随共济失调、发作性眩晕患者,术后症状无明显改善,但无进一步脑卒中发作.彩色多普勒超声复查显示:治疗部位狭窄率＞50%5例,再狭窄发生率20.8%.按Malek评分法评定,1分22例,2分1例,4分1例.结论 应用血管内支架成形术治疗颅外椎动脉狭窄是安全、有效的.通过技术改进可以在一定程度上降低再狭窄率.

Abstract：

Objectives To evaluate the safety and efficacy of endovascular angioplasty for extracranial vertebral artery ( VA ) stenosis caused by atherosclerosis. Methods We analyzed retrospectively data of the 24 patients with extracranial vertebral artery stenosis who had been placed endovascular angioplasty from April 2006 to March 2010. According to Mori classification, there were 21 type A and 3 type B among all cases.The artery stenosis rate was 60％ -95％ , the average was 79％ ± 10％. Results Twenty-four balloon mounted stents were placed, the successful rate was 100％. Postoperatively the stenosis rate decreased to 4％ ± 6％. Patients were followed up from 3 to 36 months, the average was 22 months. Symptomes disappeared in 15 out of 17 patients. Postoperative restenosis on the treatment site with transient brain ischemia occurred in one patient. The symptoms in another patient of multiple cerebral infarction with ataxia and episodic vertigo were not relieved, although the patient didn't suffer from apoplectic seizure after the intervention. Postoperative color Doppler ultrasound revealed an over 50％ residual stenosis in 5 patients. The postoperative restenosis rate was 20. 8％. According to Malek scoring, 22 patients were scored 1 point, 1 patient scored 2 and one scored 4. Conclusions Endovascular angioplasty with stent placement is a safe and effective treatment. The restenosis rate could be futher reduced by technology improvement.

Endovascular angioplasty for extracranial vertebral artery stenosis caused by atherosclerosis

Objectives To evaluate the safety and efficacy of endovascular angioplasty for extracranial vertebral artery ( VA ) stenosis caused by atherosclerosis. Methods We analyzed retrospectively data of the 24 patients with extracranial vertebral artery stenosis who had been placed endovascular angioplasty from April 2006 to March 2010. According to Mori classification, there were 21 type A and 3 type B among all cases.The artery stenosis rate was 60％ -95％ , the average was 79％ ± 10％. Results Twenty-four balloon mounted stents were placed, the successful rate was 100％. Postoperatively the stenosis rate decreased to 4％ ± 6％. Patients were followed up from 3 to 36 months, the average was 22 months. Symptomes disappeared in 15 out of 17 patients. Postoperative restenosis on the treatment site with transient brain ischemia occurred in one patient. The symptoms in another patient of multiple cerebral infarction with ataxia and episodic vertigo were not relieved, although the patient didn't suffer from apoplectic seizure after the intervention. Postoperative color Doppler ultrasound revealed an over 50％ residual stenosis in 5 patients. The postoperative restenosis rate was 20. 8％. According to Malek scoring, 22 patients were scored 1 point, 1 patient scored 2 and one scored 4. Conclusions Endovascular angioplasty with stent placement is a safe and effective treatment. The restenosis rate could be futher reduced by technology improvement.