| 肝动脉超选灌注自体骨髓干细胞治疗失代偿期乙型肝炎肝硬化的临床研究 |
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| 引用本文： | 金波,孟繁平,冯宇,文凤,贾雪红,马雪梅,张敏,高银杰,向轶,汤汝佳,王华明,马威,李捍卫,王慧芬. 肝动脉超选灌注自体骨髓干细胞治疗失代偿期乙型肝炎肝硬化的临床研究[J]. 传染病信息, 2011, 24(3): 143-146 |
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| 作者姓名： | 金波 孟繁平 冯宇 文凤 贾雪红 马雪梅 张敏 高银杰 向轶 汤汝佳 王华明 马威 李捍卫 王慧芬 |
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| 作者单位： | 解放军第三○二医院肝硬化诊疗中心,北京,100039;解放军第三○二医院肝移植研究中心,北京,100039;解放军第三○二医院医学影像中心,北京,100039;解放军第三○二医院肝衰竭诊疗与研究中心,北京,100039 |
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| 基金项目： | 国家十一五科技重大专项 |
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| 摘 要： | 目的 分析肝动脉超选灌注自体骨髓干细胞对失代偿期乙型肝炎(乙肝)肝硬化患者的疗效及安全性.方法 选择失代偿期乙肝肝硬化患者20例,从髂后上棘抽取骨髓,体外分离纯化骨髓源性干细胞,通过肝动脉超选注入肝脏,在移植后2、4、8、12周复查肝功能,观察实验室指标变化及不良反应情况.同时选取常规治疗的失代偿期乙肝肝硬化患者20例...
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| 关 键 词： | 骨髓干细胞 肝动脉超选 肝硬化 |
Treatment with superselective hepatic artery infusion of autologous bone marrow stem cells in patients with HBV-related decompensated cirrhosis |
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| JIN Bo,MENG Fan-ping,FENG Yu,WEN Feng,JIA Xue-hong,MA Xue-mei,ZHANG Min,GAO Yin-jie,XIANG Yi,TANG Ru-jia,WANG Hua-ming,MA Wei,LI Han-wei,WANG Hui-fen. Treatment with superselective hepatic artery infusion of autologous bone marrow stem cells in patients with HBV-related decompensated cirrhosis[J]. Infectious Disease Information, 2011, 24(3): 143-146 |
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| Authors: | JIN Bo MENG Fan-ping FENG Yu WEN Feng JIA Xue-hong MA Xue-mei ZHANG Min GAO Yin-jie XIANG Yi TANG Ru-jia WANG Hua-ming MA Wei LI Han-wei WANG Hui-fen |
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| Affiliation: | JIN Bo,MENG Fan-ping,FENG Yu,WEN Feng,JIA Xue-hong,MA Xue-mei,ZHANG Min,GAO Yin-jie,XIANG Yi,TANG Ru-jia,WANG Hua-ming,MA Wei,LI Han-wei *,WANG Hui-fen * Liver Cirrhosis Treatment Center,302 Hospital of PLA,Beijing 100039,China |
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| Abstract: | Objective To analyze the efficacy and safety of treatment with superselective hepatic artery infusion of autologous bone marrow stem cells(BMSC) in patients with HBV-related decompensated cirrhosis.Methods Bone marrow was aspirated from poster superior spine of 20 adult patients with HBV-related decompensated cirrhosis(BMSC treatment group).After isolation and pu-rification in vitro,the stem cells were injected into liver via hepatic artery.The liver function parameters,laboratory parameters and side effect... |
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| Keywords: | bone marrow stem cells superselective hepatic artery infusion liver cirrhosis |
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