丙泊酚复合瑞芬太尼靶控静脉麻醉用于胆囊切除手术的临床观察

目的评价丙泊酚复合瑞芬太尼靶控静脉麻醉的诱导和术后苏醒过程。方法ASAI-Ⅱ级择期行胆囊切除手术患者40例，随机分为瑞芬太尼（R）组及芬太尼（F）组，R组采用瑞芬太尼和丙泊酚诱导和维持麻醉，F组采用芬太尼和丙泊酚诱导和维持麻醉，观察并比较两组患者麻醉诱导及维持期血流动力学的变化、术毕停药后患者自主呼吸恢复时间、清醒时间、拔管时间以及苏醒期不良反应等。结果瑞芬太尼麻醉术中循环波动较小，苏醒快，术后并发症少。结论与芬太尼相比，瑞芬太尼可更安全有效地用于胆囊切除术。

Propofol target-controlled intravenous remifentanil anesthesia for cholecystectomy clinical observation

Objective To evaluate the hemodynamics during induction of anesthesia and recovery profiles following target-controled infusion-based anesthesia using remifentanil and propofol. Methods ASA Ⅰand Ⅱ elective gallbladder surgery patients in 40 cases were randomly divided into remifentanil（R） group and fentanyl（V） group. Group R were induced and maintained with remifentanil and propofol,while group F with fentanyl and propofol. Hemadynamics changing during the induction and maintenance phase ,spontaneous breath recovery time,awake time, time of endotracheal tube extubation and side-effect were investigated and compared. Results Remifentanil anesthesia resulted in less circulatory disturbance,faster recovery and less post-operative complications. Conclusion Compared with fentanyl, remifentanil can be used more safely and effectively in cholecy stectomy.