| 细胞膜隧道纳米管及其意义 |
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| 引用本文： | 吴克复,宋玉华,马小彤. 细胞膜隧道纳米管及其意义[J]. 白血病．淋巴瘤, 2009, 18(4): 195-196. DOI: 10.3760/cma.j.issn.1009-9921.2009.04.002 |
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| 作者姓名： | 吴克复 宋玉华 马小彤 |
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| 作者单位： | 中国医学科学院北京协和医学院,血液学研究所血液病医院,实验血液学国家重点实验室,天津,300020 |
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| 摘 要： | 隧道纳米管（TNT）是新发现的细胞间通讯和传递机制，在免疫反应和病毒传播中起重要作用，还可能参与胚胎发育、基因表达调节和肿瘤发生发展等基本生物学过程。现在采用的观察TNT的方法均较复杂，该文介绍采用常用的组织化学方法经过碘酸-Shiff染色（简称PAS反应）观察细胞滴片的TNT，研究白血病、淋巴瘤患者体液标本的TNT。
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| 关 键 词： | 隧道纳米管 细胞间通讯 白血病 细胞 |
| 收稿时间： | 2009-03-24; |
Cellular tunneling nanotubes and its significance |
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| WU Ke-fu,SONG Yu-hua,MA Xiao-tong. Cellular tunneling nanotubes and its significance[J]. Journal of Leukemia & Lymphoma, 2009, 18(4): 195-196. DOI: 10.3760/cma.j.issn.1009-9921.2009.04.002 |
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| Authors: | WU Ke-fu SONG Yu-hua MA Xiao-tong |
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| Affiliation: | Institute of Hematology, Chinese Academy of Medical Sciences, Tianjin |
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| Abstract: | Tunneling nanotubes(TNT) are cellular communication and transport mechanism discovered recently. TNTs play important role in immunological response and viral spread, also may involve embryonic development, regulation of gene expression and carcinogenesis. However, it was not easy to study TNT for clinical samples since intricate assay method for TNT. We suggested using histochemical assay PAS staining in cell drip to show TNT in leukemia and lymphoma samples. |
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| Keywords: | Tunneling nanotubes Cellular communication Leukemia Cell |
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