| 参草通脉颗粒丹参酮ⅡA提取工艺研究 |
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| 引用本文： | 黄忠钧,张艳,孟庆生,肖雪,王思尹. 参草通脉颗粒丹参酮ⅡA提取工艺研究[J]. 中国现代药物应用, 2012, 6(20): 8-9 |
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| 作者姓名： | 黄忠钧 张艳 孟庆生 肖雪 王思尹 |
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| 作者单位： | 1. 沈阳市沈河区妇婴医院,110011
2. 辽宁中医药大学附属医院 |
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| 摘 要： | 目的参草通脉颗粒在临床中治疗慢性心衰疗效确切,有效率达到90%以上,为了进一步明确中药的疗效成分便于推广研究。我们探讨其主要药物丹参中丹参酮ⅡA的最佳醇提取工艺条件,为丹参药材的综合利用提供实验依据。方法采用正交试验法,以丹参酮ⅡA的提取量及浸膏得率为考察指标,优选回流法提取的最佳工艺条件。结果最佳提取工艺为:以10倍量80%乙醇回流提取3次,每次1h。结论优选的提取工艺设计合理,丹参酮ⅡA提取率较高。
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| 关 键 词： | 丹参 丹参酮ⅡA 提取 工艺 |
Study on extract process of tanshinone A in Salvia miltiorrhiza Bge |
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| Affiliation: | HUANG Zhong-jun, ZHANG Yan, MENG Qing-sheng , et al. Shenhe District Women＇ s and Children＇ s Hospital in Shenyang , Shenyang 110011, Chi- |
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| Abstract: | Objective To develop comprehensive utilization of Salvia miltiorrhiza to explore the best conditions of extract Tanshinone A in Salvia miltiorrhiza Bge by ethanol. Methods With tanshinone A and Yield of extract as index, optimization of reflux to the optimum conditions. Results The optimal refluxing was to extract ten times with 80% alcohol. Conclusion Optimization extraction process design is reasonable, ex- traction rate of Tanshinone is higher. |
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| Keywords: | Salvia miltiorrhiza bge Tanshinone A Extract Technology |
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