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Focal intracerebral accumulation of a novel type of amyloid protein |
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| Authors: | A Hori T Kitamoto J Tateishi P Hann R L Friede |
| Institution: | (1) Abteilung für Neuropathologie, Universität Göttingen, D-3400 Göttingen, Germany;(2) Department of Neuropathology, Neurological Institute, Kyushu University, Japan;(3) Institut für Neuropathologie, Medizinische Hochschule Hannover, Konstanty-Gutschow-Strasse 8, D-3000 Hannover 61, Germany |
| Abstract: | Summary The brain of a 60-year-old patient with bronchial carcinoma presented a focal amyloid deposit in the white matter associated with myelin and axonal destruction. An additional lesion was found in the basal ganglia. This silent focal intracerebral accumulation of amyloid substance may be a prestadium of a  cerebral amyloidoma . The histochemical chemical and immunohistochemical analysis of the accumulated amyloid indicated that it may belong to a novel type of amyloid. |
| Keywords: | Amyloidosis Cerebral amyloid Cerebral amyloidoma |
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