中药通心络对糖尿病微血管病变防治研究

糖尿病微血管病变是糖尿病慢性并发症的病理基础,发病机制与多元醇代谢异常、糖化反应的亢进、氧化应激、蛋白激酶C激活、己糖胺通路激活等几个途径相关。通过中药通心络作用于以上几个途径来对其进行防治,可有效改善糖尿病患者的微血管病变,总结了通心络对其系统效应的研究结果。提高糖尿病微血管病变患者机体自适应、自调节、自修复、自稳态的能力等系统特征学改变,进而达到临床上防治糖尿病微血管病变的良好作用。

Prevention Effects of Tongxinluo on Microvessel Disease Induced by Diabetes Mellitus

Microvessel diseases are a basic pathology of diabetes.The pathological mechanism is related to various factors,such as hyperglycemia abnormal metabolism of polyethanol,nonenzymatic glycation,apoptosis,activated DG2,PKC system,hexosamine biosynthesis pathway.tongxinluo can improve microvessel diseases of diabetic patient by preventing and affecting above several signal pathways.therefore,our paper summarizes the system effectiveness of Tongxinluo:including to enhance the ability of self-adaptation,self-regu...