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| 呆聪液对老龄大鼠痴呆模型免疫功能的影响 | |
| 引用本文： | 赵淑梅,岳启安,左凤英,高敬宗,李光宗,尤敏. 呆聪液对老龄大鼠痴呆模型免疫功能的影响[J]. 潍坊医学院学报, 2000, 22(1): 11-12 |
| 作者姓名： | 赵淑梅 岳启安 左凤英 高敬宗 李光宗 尤敏 |
| 作者单位： | 1. 潍坊医学院微生物学教研室,潍坊,261042 2. 潍坊医学院临床教学部,潍坊,261042 3. 潍坊医学院中医学教研室,潍坊,261042 4. 潍坊医学院解剖学教研室,潍坊,261042 |
| 基金项目： | 山东省中医管理局省中医科技发展基金资助(批准号98024) |
| 摘 要： | 目的 探讨中药呆聪液对老龄鼠痴呆模型免疫功能的影响。方法 选择２２月龄的老龄大鼠，用双侧电解损毁脑基底核法，造成学习和记忆功能障碍的痴呆动物模型，用＾３Ｈ－ＴｄＲ掺入ＤＮＡ法试验了呆聪液对淋巴细胞增殖的影响，用脾细胞介导红细胞溶血的紫外 光度计测定法测定脾细胞抗体产生能力，结果 呆聪液明显提高痴呆动物的淋巴细胞增殖能力。与模型组比较差异显著，还明显提高脾细胞抗体产生能力，与模型组比较差异显著。结论 |
| 关 键 词： | 呆聪液 淋巴细胞增殖 体液免疫 老年性痴呆 |
| 修稿时间： | 1999-10-10 |
The Effect of Daicong Solution on Immune Function for Aged Rat Dementia Model |
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| Zhao Shumei,Yue Qi'an,Zuo Fengying,et al. The Effect of Daicong Solution on Immune Function for Aged Rat Dementia Model[J]. Journal of Weifang Medical College, 2000, 22(1): 11-12 | |
| Authors: | Zhao Shumei Yue Qi'an Zuo Fengying et al |
| Affiliation: | Zhao Shumei,Yue Qi'an,Zuo Fengying,et alDepartment of Microbiology,Weifang Medical College,Weifang,261042[ |
| Abstract: | Objective To explore the effect of Daicong Solution on immune function for aged rat dementia model.Method Basal nuclei of 22 month old rat were destroyed by bilateral electrolytic method have established animal dementia model of learning and memory function.Lymphocyte proliferation was tested by 3H TdR incorporation methods.Spleen cell producing antibody function was determined by spleen cell mediated red cell hemolysis method.Result Daicong Solution has remarkably increased lymphocyte proliferation function,compared with model groups (P<0.01).It has risen spleen cell producing antibody function too,compared with model group (P<0.01).Conclusion Daicong Solution have marked increased functions of cellular and humoral immunity for dementia animal model.Which is heavier than that of Naofukang. [ |
| Keywords: | Daicong Solution Dementia animal model Lymphocyte proliferation Humoral immunity |
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