| 成人珠蛋白生成障碍性贫血基因携带者的血清铁和血清铁蛋白的研究 |
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| 引用本文： | 陈丕绩,邹汉良,张松,金娴. 成人珠蛋白生成障碍性贫血基因携带者的血清铁和血清铁蛋白的研究[J]. 国际检验医学杂志, 2012, 33(14): 1703-1704 |
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| 作者姓名： | 陈丕绩 邹汉良 张松 金娴 |
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| 作者单位： | 广东省深圳市盐田区人民医院检验科,518081 |
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| 摘 要： | 目的 探讨珠蛋白生成障碍性贫血基因携带者的血清铁、血清铁蛋白的浓度,了解铁负荷的状况,为预防高铁负荷危害提供理论依据.方法 将珠蛋白生成障碍性贫血基因携带者109例,健康者151例,分别设为病例组和对照组.使用美国Beckman LH750全自动血细胞仪测定RBC、Hb、MCV、RDW,美国Beckman Synchron LX-20全自动生化仪测定血清铁,德国Roche6000全自动电化学发光测定血清铁蛋白.结果 病例组的珠蛋白生成障碍性贫血基因携带者的血清铁和血清铁蛋白和对照组的数据经统计学比较,差异有统计学意义(P<0.05).结论 珠蛋白生成障碍性贫血基因携带者体内血清铁、血清铁蛋白明显高于对照组,存在高铁负荷的状态,应加强监测铁负荷,预防高铁引起的各类并发症.
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| 关 键 词： | 地中海贫血 血清铁 血清铁蛋白 |
Research on serum iron and serum ferritin in thalassemic trait adults |
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| Chen Piji , Zou Hanliang , Zhang Song , Jin Xian. Research on serum iron and serum ferritin in thalassemic trait adults[J]. International Journal of Laboratory Medicine, 2012, 33(14): 1703-1704 |
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| Authors: | Chen Piji Zou Hanliang Zhang Song Jin Xian |
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| Affiliation: | (Laboratory Department,Yantian People’s Hospital,Shenzhen,Guangdong 518081,China) |
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| Abstract: | Objective To investigate serum levels of iron and ferritin in thalassemic trait adults.Methods 260 cases of thalassemic trait adults(case group) and 151 cases of healthy subjects(control group) were enrolled and detected for RBC,Hb,MCV,RDW by using Beckman LH750 system,for serum iron by using Beckman Synchron LX-20 system and for serum ferritin by using Roche6000 system.Results There were statistical differences in serum levels of iron and ferritin between case group and control group(P<0.05).Conclusion Serum levels of iron and ferritin in thalassemic trait adults might be higher than those in healthy subjects,indicating that there might be overloaded iron in thalassemic trait adults and monitoring of iron loading should be strengthened to prevent diseases caused by iron overloading. |
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| Keywords: | thalassemia serum iron serum ferritin |
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