1404例健康体检者肿瘤特异性生长因子检测结果调查分析

目的 探讨恶性肿瘤特异性生长因子(TSGF)在健康体检人群肿瘤筛查中的价值.方法采用全自动生化分析仪检测1 404例健康体检者血清TSGF含量.结果 各年龄段TSGF结果差异有统计学意义(P＜0.05),其中60岁以上年龄段TSGF含量最高.不同性别组比较差异无统计学意义(P＞0.05).在1 404例体检者中,阴性结果1 359例,可疑阳性34例(2.42%),阳性11例(0.78%),1个月后复检,仍有5例TSGF值落在可疑阳性值区间内,2例仍为阳性.3个月后复查,5例可疑阳性中仍有3例,但未做其他任何检查和处理,至今也未表现出临床异常.2例阳性被检者,1例转为阴性,1例阳性者确诊为肺癌.结论 在健康体检人群中进行TSGF检测,对恶性肿瘤的筛选和早期发现,具有一定的实用价值.

Investigation of tumor specific growth factor levels in 1 404 cases of healthy subjects

Objective To explore the value of tumor specific growth factor(TSGF) for cancer screening in healthy population.Methods Serum levels of tumor specific growth factor were detected by using automatic biochemical analyzer in 1 404healthy subjects.Results There was significant difference between different age groups(P<0.05),and the highest level could be detected in subjects more than 60years old.There was no significant difference between male and female(P>0.05).In all detected subjects,1 359cases were with negative result,34cases were suspected positive(2.64%),11cases were positive(0.78%).Re-examination after 1month indicated that 5cases were still suspected positive,2cases remained positive.Re-examination after 3months indicated that 3cases were suspected positive,were not performed for any inspection and treatment,and so far did not show clinical abnormalities.Among the two positive cases,one became negative,and the other one was definitely diagnosed with lung cancer.Conclusion TSGF,as an early tumor marker in healthy people,might be with practical value in the screening and early detection of malignant tumor.