2011年临床病原菌分布及耐药性分析

目的 分析某院2011年上半年临床分离病原菌的分布及耐药性.方法 采用MicroSCcan-WalkAway 40SI型自动鉴定及药敏测试系统进行菌种鉴定及药敏试验.结果 检出率前5位病原菌分别为大肠埃希菌26.07%(91株)、金黄色葡萄球菌23.78%(83株)、表皮葡萄球菌20.06%(70株)、铜绿假单胞菌16.61%(58株)、鲍曼不动杆菌13.47%(47株);病原菌敏感率大于或等于75%的抗菌药物包括亚胺培南(大肠埃希菌、铜绿假单胞菌、鲍曼不动杆菌),哌拉西林/他唑巴坦(铜绿假单胞菌、金黄色葡萄球菌),复方新诺明(嗜麦芽窄食单胞菌),丁胺卡那霉素(鲍曼不动杆菌),利福平、奎奴普丁/达福普丁、吗啉恶酮、万古霉素(金黄色葡萄球菌).结论 该院常见病原菌的耐药性持续增强,应科学规范使用抗菌药物.

Distribution and drug resistance of pathogenic bacteria in 2011

Objective To investigate the distribution and drug resistance of pathogenic bacteria in certain area from Jan.to Jun.in 2011.Methods Pathogenic bacteria were identified and detected by MicroSCcan-WalkAway 40SI automated identification and susceptibility testing system.Results Results The top five pathogens were Escherichia coli 26.07%(91 strains),Staphylococcus aureus 23.78%(83 strains),Staphylococcus epidermidis 20.06%(70 strains),Pseudomonas aeruginosa 16.61%(58 strains) and Acinetobacter baumanii 13.47%(47 strains).Antibacterials with sensitivity more or equal with 75% included Imipenem(Escherichia coli,Pseudomonas aeruginosa and Acinetobacter baumanii),Piperacillin/Tazobactam(Pseudomonas aeruginosa and Staphylococcus aureus),Trimethoprim-Sulfamethoxazole(Stenotrophomonas maltophilia),Amikacin(Acinetobacter baumanii),Rifampicin,Quinupristin/Dalfopristin,Linezolid and Vancomycin(Staphylococcus aureus).Conclusion Drug resistance of common pathogenic bacteria enhanced persistently,and antibacterials should be rationally used.