| 1710例女性不孕患者血清抗体检测结果分析 |
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| 引用本文： | 赵军,周运恒.1710例女性不孕患者血清抗体检测结果分析[J].国际检验医学杂志,2012,33(9):1060-1061,1063. |
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| 作者姓名： | 赵军 周运恒 |
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| 作者单位： | 武警上海总队医院检验科,上海,201103 |
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| 基金项目： | 上海市长宁区卫生局临床课题资助项目 |
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| 摘 要： | 目的 探讨各种血清抗体与女性免疫性不孕的关系.方法 用ELISA法对不孕的1 710例妇女血清进行抗精子抗体(ASAb)、抗子宫内膜抗体(EMAb)、抗卵巢抗体(AOAb)检测.结果 患者血清中ASAb、EMAb、AOAb阳性率分别为29.77%、29.77%、30.53%,与对照组比较,差异有统计学意义(P<0.05).结论 免疫性不孕患者血清中各种抗体可影响妊娠的不同环节,导致不孕;血清抗体的联合检测可以为临床诊断免疫性不孕提供科学依据.
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| 关 键 词： | 不育 精子 子宫内膜 卵巢 抗体 酶联免疫吸附测定 |
Analysis on serum antibody in 1 710 female patients with infertility |
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| Zhao Jun
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Zhou Yunheng.Analysis on serum antibody in 1 710 female patients with infertility[J].International Journal of Laboratory Medicine,2012,33(9):1060-1061,1063. |
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| Authors: | Zhao Jun Zhou Yunheng |
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| Institution: | (Department of Clinical Laboratory,Shanghai Crops Hospital of Chinese People′s Armed Police,Shanghai 201103,China) |
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| Abstract: | Objective To investigate the relationship between serum antibody and immunologic infertility.Methods Serum anti-sperm antibody,anti-endometrial antibody and anti-ovarian antibody in 1 710 female patients with primary or secondary infertility were tested by enzyme linked immunosorbent assay(ELISA).Results The positive rates of the above antibodies were 29.77%,29.77% and 30.53% respectively,and were all significantly higher than those in control group(P<0.05).Conclusion Serum antibody might influence the various component element of pregnancy.Combined detection of serum antibodies could be valuable for the diagnosis of immunologic infertility. |
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| Keywords: | infertility spermatozoa endometrium ovary antibodies enzyme-linked immunosorbent assay |
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