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Reversion of the ELISPOT test after treatment in Gambian tuberculosis cases
Authors:Alexander M Aiken   Philip C Hill   Annette Fox   Keith PWJ McAdam   Dolly Jackson-Sillah   Moses D Lugos   Simon A Donkor   Richard A Adegbola  Roger H Brookes
Affiliation:(1) Tuberculosis Division, Medical Research Council Laboratories, Banjul, The Gambia
Abstract:

Background  

New tools are required to improve tuberculosis (TB) diagnosis and treatment, including enhanced ability to compare new treatment strategies. The ELISPOT assay uses Mycobacterium tuberculosis-specific antigens to produce a precise quantitative readout of the immune response to pathogen. We hypothesized that TB patients in The Gambia would have reduced ELISPOT counts after successful treatment.
Keywords:
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