| 慢性肾衰脂质过氧化异常和微量元素相关的研究 |
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| 引用本文： | 韩颖敏,张庆怡.慢性肾衰脂质过氧化异常和微量元素相关的研究[J].上海交通大学学报(医学版),1995,15(2):101-104. |
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| 作者姓名： | 韩颖敏 张庆怡 |
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| 作者单位： | 上海第二医科大学附属仁济医院肾脏科 |
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| 摘 要： | 对３０便慢性肾衰（ＣＲＦ）患者作血清及红细胞中超氧歧化酶（ＳＯＤ）、血清丙二醛（ＭＤＡ）及多种微量元素的测定，结果显示：ＣＲＦ患者血清ＭＤＡ水平显著升高，血透和非透析组血清锌的下降与红细胞ＳＯＤ活性下降正相关，腹透组血清铝的升高与红细胞ＳＯＤ活性下降负相关，血透患者透析后ＳＯＤ活性较透析前明显升高。
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| 关 键 词： | 慢性 肾功能衰竭 超氧化物歧化酶 微量元素 |
Lipid Peroxidation Abnormalities and Their Correlation with Trace Elements in Chronic Renal Failure Patients |
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| Han Yingmin, et al.Lipid Peroxidation Abnormalities and Their Correlation with Trace Elements in Chronic Renal Failure Patients[J].Journal of Shanghai Jiaotong University:Medical Science,1995,15(2):101-104. |
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| Authors: | Han Yingmin |
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| Abstract: | We determined the plasma superoxide dismutase(SOD),erythrocyte SOD,plasma levels of malonyl-dialdehyde(MDA)and plasma Zinc(Zn),copper(Cu),selenium(Se),aluminium(Al)and cadium(Cd)in 30 chronic renal failure(CRF)patients. The results showed: plasma Zn,Se,SOD activity and RBC-SOD activity were significantly low in CRF,while plasma Al and MDA were elevated.There was a positive correlation between the plasma Zn levels and RBC-SOD activity in the hemodialyzed and nondialyzed uremic patients. There was also a negative correlation between plasma Al levels and RBC-SOD activity which tends to improve after a single hemodialysis. |
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| Keywords: | trace elements superoxide dismutase malonyl-dialdehyde |
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