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Animal model: The mode of inheritance of craniomandibular osteopathy in west highland white terrier dogs
Authors:George A. Padgett  Ulreh V. Mostosky  David J. Prieur
Abstract:Craniomandibular osteopathy is a disease of several breeds of dogs, principally West Highland White and Scottish terriers. It is characterized by a non-neoplastic proliferation of bone on the ramus of the mandible and/or the tympanic bulla. The disease in various respects resembles Paget's disease and infantile cortical hyperrostosis of humans. A retrospective pedigree analysis of a kindred of West Highland White terriers was performed to determine if the trait was inherited and to determine mode of inheritance. This study indicated that in West Highland White terriers, the condition is an autosomal recessive trait.
Keywords:autosomal recessive trait  animal model (canine)  non-neoplastic proliferation of bone  Paget's disease  infantile cortical hyperostosis  craniomandibular osteopathy
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