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| 高压氧对脊髓损伤大鼠脊髓组织中超氧化物歧化酶和过氧化氢酶活性的影响 | |
| 引用本文： | 方健,侯铁胜,方以群,陈勇,李斌,傅强,陈文笔,刘景昌. 高压氧对脊髓损伤大鼠脊髓组织中超氧化物歧化酶和过氧化氢酶活性的影响[J]. 解放军医学杂志, 2002, 27(9): 821-822 |
| 作者姓名： | 方健 侯铁胜 方以群 陈勇 李斌 傅强 陈文笔 刘景昌 |
| 作者单位： | 1. 230031,合肥,解放军第105医院 2. 上海长海医院 3. 海军医学研究所 4. 解放军第123医院 |
| 基金项目： | 全军医学重点实验室基金资助课题 (编号 0 37) |
| 摘 要： | 通过复制大鼠脊髓损伤（SCD）模型，探讨高血压（HBO）治疗对脊髓组织中氧化物歧化酶（SOD）及过氧化氢酶（CAT）活性的影响。结果显示，损伤后，脊髓组织中SOD及CAT活性明显下降，0.25Mpa HBO及0.25MPaHBO 激素治疗后SOD及CAT活性明显恢复。提示HBO可提高脊髓组织中的抗氧化酶活性，阻止或减轻自由基的损伤，恢复脊髓组织的功能。 |
| 关 键 词： | 脊髓损伤 高压氧 超氧化物歧化酶 过氧化氢酶 |
| 修稿时间： | 2002-02-26 |
EFFECT OF HYPERBARIC OXYGEN ON ACTIVITY OF SUPEROXYGEN DISMUTASE AND CATALASE IN SPINAL CORD TISSUES AFTER SPINAL CORD INJURY |
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| Fang Jian,Hou Tiesheng,Fang Yiqun et al. Hospital of PLA,Hefei. EFFECT OF HYPERBARIC OXYGEN ON ACTIVITY OF SUPEROXYGEN DISMUTASE AND CATALASE IN SPINAL CORD TISSUES AFTER SPINAL CORD INJURY[J]. Medical Journal of Chinese People's Liberation Army, 2002, 27(9): 821-822 | |
| Authors: | Fang Jian Hou Tiesheng Fang Yiqun et al. Hospital of PLA Hefei |
| Affiliation: | Fang Jian,Hou Tiesheng,Fang Yiqun et al. 105 Hospital of PLA,Hefei 230031 |
| Abstract: | To study the effect of hyperbaric oxygen (HBO) on the activity of superoxygen dismutase (SOD) and catalase (CAT) in spinal cord tissue, a rat spinal cord injury (SCI) model was established. The results showed that the activity of SOD and CAT in the spinal cord decreased significantly after injury, bat recovered after the treatment with 0 25MPa HBO and 0 25MPa HBO+hormone. These results suggest that HBO can increase the activity of anti oxidase in spinal cord,and prevent or relieve the injury by free radicals. Thus it can recover the function of spinal cord. |
| Keywords: | spinal cord injury hyperbaric oxygenation superoxide dismutase catalase |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |