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Sertraline‐induced potentiation of the CYP3A4‐dependent neurotoxicity of carbamazepine: An in vitro study
Authors:Chaitali Ghosh  Mohammad Hossain  Addison Spriggs  Arnab Ghosh  Gerald A. Grant  Nicola Marchi  Emilio Perucca  Damir Janigro
Affiliation:1. Cerebrovascular Research, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, U.S.A;2. Department of Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, U.S.A;3. Department of Bio‐medical Engineering, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, U.S.A;4. Department of Pathobiology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, U.S.A;5. Department of Neurosurgery and Neurobiology, Stanford University School of Medicine, Stanford, California, U.S.A;6. Laboratory of Cerebrovascular Mechanisms of Brain Disorders, Department of Neuroscience, Institute of Functional Genomics, CNRS, Montpellier, France;7. Department of Internal Medicine and Therapeutics, University of Pavia and C. Mondino National Neurological Institute, Pavia, Italy;8. Department of Neurosurgery, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, U.S.A
Abstract:
Keywords:CYP3A4  Cytotoxicity  Drug interaction  Human  Ketoconazole  Neurotoxicity
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