杭州地区3621例育龄妇女TORCH感染现状分析

目的对杭州地区育龄期妇女TORCH筛查结果进行分析,为预防TORCH感染和做好优生优育工作提供临床指导。方法选取2017年1月-2018年1月在杭州师范大学附属医院进行孕前筛查和孕期普查的育龄妇女共3621例,应用化学免疫法测定血清中弓形虫IgG抗体(TOX-IgG)、弓形虫IgM抗体(TOX-IgM),风疹IgG抗体(RUV-IgG)、风疹IgM抗体(RUV-IgM),巨细胞IgG抗体(CMV-IgG)和巨细胞IgM抗体(CMV-IgM)。结果在IgM中CMV-IgM阳性率最高,为1.13%;TOX-IgM和RUV-IgM阳性率分别为0.08%和0.69%;TOX-IgG、RUV-IgG和CMV-IgG阳性率分别为2.04%、45.90%和91.49%。在育龄人群各年龄组间,20岁~29岁低龄产妇RUV-IgM、RUV-IgG、CMV-IgM和CMV-IgG阳性率最高。结论杭州市育龄妇女人群中存在一定比例的TORCH现状感染及较高CMV-IgM、CMV-IgG阳性率,建议育龄妇女孕前进行TORCH筛查。

Analysis of TORCH infection in 3621 women of childbearing age in Hangzhou

Objective To analyze the results of TORCH screening among women of childbearing age in Hangzhou,so as to provide clinical guidance for preventing TORCH infection and improving eugenic and fertility.Methods A total of 3621 women of childbearing age who underwent prenatal screening and prenatal screening in the Affiliated Hospital of Hangzhou Normal University from January 2017 to January 2018 were selected.Serum Toxoplasma IgG(TOX-IgG),Toxoplasma IgM(TOX-IgM),rubella IgG(RUV-IgG),rubella IgM(RUV-IgM),giant cell IgG(CMV-IgG)and giant cell IgM(CMV-IgM)were determined by chemical immunoassay.Results The positive rate of CMV-IgM was the highest(1.13%),the positive rates of TOX-IgM and RUV-IgM were 0.08%and 0.69%,and the positive rates of TOX-IgG,RUV-IgG and CMV-IgG were respectively 2.04%,45.90%and 91.49%.Among all the reproductive age group,the positive rates of RUV-IgM,RUV-IgG,CMV-IgM and CMV-IgG were the highest in 20-29 years old puerperal group.Conclusion There is a certain proportion of TORCH infection among women of childbearing age in Hangzhou,and the positive rates of CMV-IgM and CMV-IgG are higher.It is suggested that TORCH screening be carried out before pregnancy for women of childbearing age.