颅脑CT及磁共振弥散峰度成像对急性一氧化碳中毒迟发性脑病的预测价值研究

目的 研究颅脑CT及磁共振弥散峰度成像(DKI)对急性一氧化碳中毒迟发性脑病(DEACMP)的预测价值.方法 纳入我院急性一氧化碳中毒病例188例,所有患者均于一氧化碳中毒7d内接受颅脑CT、DKI检查.记录188例患者颅脑CT表现及DKI扫描不同ROI(额叶、顶叶、枕叶、颞叶、半卵圆中心前部、半卵圆中心后部、胼胝体膝...

Predictive Value of Brain CT and Magnetic Resonance Diffusion Kurtosis Imaging on Delayed Encephalopathy after Acute Carbon Monoxide Poisoning

Objective To study the predictive value of brain CT and magnetic resonance diffusion kurtosis imaging(DKI)on delayed encephalopathy after acute carbon monoxide poisoning(DEACMP).Methods 188 cases of patients with delayed encephalopathy after acute ca rbon monoxide poisoning in our hospital were included.All patients underwent brain CT and DKI within 7 d of ca rbon monoxide poisoning.The cranial CT findings and AK values of DKI scan of different ROIs(frontal lobe,parietal lobe,occipital lobe,temporal lobe,anterior centrum semiovale,posterior centrum semi ovale,corpus callosum knee,corpus callosum stem,corpus callosum splenium)were recorded among the 188 patients.At 3 months of follow-up,the patients were divided into DEACMP group and non-DEACMP group according to whether DEACMP occurred.The abnormal rate of brain CT detection and the AK values of different ROIs were compared between the two groups.Results At 3 months of follow-up,56 cases were included in DEACMP group and 132 cases in non-DEACMP group according to the relevant diagnostic criteria.In DEACMP group,there were 47 abnormal cases and 9 normal cases by brain CT detection.In non-DEACMP group,there were 31 abnormal cases and 101 normal cases.The sensitivity,specificity,accuracy rate,positive predictive value,and negative predictive value of predicting DEACMP were83.93%,88.64%,87.23%,75.81%,and 92.86%respectively.The AK values of frontal lobe,parietal lobe,occipital lobe,temporal lobe,anterior centrum semi ovale,posterior centrum semi ovale,corpus callosum knee,corpus callosum stem,and corpus callosum splenium in DEACMP group were higher than those in non-DEACMP group(P<0.05).Conclusion Brain CT has good specificity in predicting DEACM P,and the increase of DKI parameter AK value also has certain predictive value on DEACMP.