MDCT与MRI对经肝动脉化疗栓塞治疗肝细胞肝癌疗效评价的对比研究

目的对比多排螺旋CT(MDCT)和磁共振成像(MRI)对肝细胞肝癌(HCC)患者经肝动脉化疗栓塞(TACE)临床疗效的评估价值。方法纳入90例经TACE治疗3~5次的HCC患者,数字血管造影(DSA)、MDCT和MRI对HCC患者最后一次TACE后进行检测,以DSA检测结果作为评比标准,比较MDCT和MRI对HCC患者TACE术后病灶残余或复发以及肿瘤包膜的检出情况。结果 90例HCC患者TACE后,DSA检出86个病灶残余或复发,46个病灶无残余或复发;MDCT检出64个病灶残余或复发,未检出病灶22个,检测准确率为83.3%,敏感性为74.4%,特异度为100.0%;MRI检出82个病灶残余或复发,未检出病灶4个,检测准确率为97.0%,敏感性为95.3%,特异度为100.0%。DSA、MDCT和MRI检出肿瘤包膜的数目分别为132个(100.0%)、12个(9.1%)和46个(34.8%)。结论 MRI评估HCC患者TACE术后疗效要优于MDCT。

Comparative Study of MDCT and MRI in the Treatment of Hepatocellular Carcinoma with Transcatheter Arterial Chemoembolization

Objective To compare the clinical efficacy of multi-slice spiral CT(MDCT) and magnetic resonance imaging(MRI) in patients with hepatocellular carcinoma(HCC) treated with transcatheter arterial chemoembolization(TACE).Methods 90 patients with HCC who were treated with TACE for 3 and 5 times were enrolled in this study.DSA,MDCT,and MRI were used to detect TACE after the last time in HCC patients.The results of DSA were used as the evaluation criteria.The detection of residual or recurrent lesions and tumor capsule in HCC patients after TACE was compared by MDCT and MRI.Results 90 patients with HCC after TACE,86 lesions were found to be residual or recurrent in DSA,and no residual or recurrent lesions were found in 46 lesions.64 lesions were detected by MDCT,and 22 lesions were not detected.The accuracy,sensitivity and specificity of MDCT were 83.3%,74.4%,and 100.0%,respectively,The detection accuracy,sensitivity,and specificity were 97.0%,95.3% and 100.0%,respectively.The number of tumor envelope detected by DSA,MDCT and MDCT were 132(100.0%),12(9.1%) and 46(34.8%).Conclusion MRI is superior to MDCT.in evaluating the postoperative efficacy of TACE in patients with HCC.