联合检测血清淀粉样蛋白A和降钙素原在胎膜早破孕妇羊膜腔感染中的诊断价值

目的探讨检测血清淀粉样蛋白A(SAA)和降钙素原(PCT)对胎膜早破(PROM)孕妇合并羊膜腔感染的诊断价值。方法收集2017年9月-2018年9月本院住院分娩的胎膜早破孕妇120例为实验组,其中足月胎膜早破(TPROM)孕妇和足月前胎膜早破(PPROM)孕妇各60例;同时收集同期在本院住院行择期剖宫产分娩的足月孕妇60例为对照组,检测SAA和PCT在2组中的表达情况。结果实验组中羊膜腔感染率为42.5%,对照组为3.3%,2组相比差异有统计学意义(P<0.05);SAA和PCT在实验组的平均表达量高于对照组,且两者在PPROM组的平均表达量高于TPROM组,差异均有统计学意义(P<0.05);SAA和PCT联合检测的敏感度和特异度高于两者单独检测的敏感度和特异度。结论联合检测血清SAA和PCT对胎膜早破孕妇羊膜腔感染具有较高的诊断价值。

The value of combined detection of serum serum amyloid A and procalcitonin in amniotic infection of pregnant women with premature rupture of membranes

Objective To investigate the value of serum serum amyloid A(SAA)and procalcitonin(PCT)in amniotic infection of pregnant women with premature rupture of membranes(PROM).Methods A total of 120 pregnant women who suffered premature rupture of membranes and hospitalized in our hospital delivery were collected as the experimental group during September 2017-September 2018,including 60 pregnant women with TPROM and 60 pregnant women with PPROM.60 patients with full-term pregnant women who underwent elective cesarean delivery in our hospital at the same time were used as the control group to detect the expressions of SAA and PCT in the two groups.Results The amniotic infection rate was 42.5%in the experimental group and 3.3%in the control group,and the difference between the two groups was statistically significant(P<0.05).The average expression of SAA and PCT in the experimental group was higher than that in the control group,and the difference between the two groups was statistically significant(P<0.05).The expressions of SAA and PCT in the PPROM group were higher than that in the TPROM group,with the differences statistically significant(P<0.05).The sensitivity and specificity of the combined detection of SAA and PCT were higher than the sensitivity and specificity of the two separate tests.Conclusion Combined detection of serum SAA and PCT has a high diagnostic value for amniotic infection in pregnant women with premature rupture of membranes.