Peptidergic Regulation of Thymocyte Differentiation, Proliferation, and Apoptosis during Aging of the Thymus |
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| Authors: | N. S. Lin��kova V. O. Polyakova A. V. Trofimov I. M. Kvetnoy V. Kh. Khavinson |
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| Affiliation: | St. Petersburg Institute of Bioregulation and Gerontology, North Western Division of Russian Academy of Medical Sciences, Russia. miayy@yandex.ru |
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| Abstract: | The effects of T-31, AB-17, and AB-9 peptides on old (passage 8) thymocyte culture were studied. Only AB-9 peptide exhibited a complex geroprotective effect on thymocytes during their aging. Peptide AB-9 stimulated proliferative activity and differentiation of thymocytes and inhibited their apoptosis. |
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