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高效液相色谱法测定更昔洛韦凝胶的含量
引用本文:王海英.高效液相色谱法测定更昔洛韦凝胶的含量[J].黑龙江医药科学,2009,32(3):26-26.
作者姓名:王海英
作者单位:大庆市第二医院药剂科,黑龙江,大庆,163461
摘    要:目的:建立测定更昔洛韦凝胶含量的高效液相色谱法。方法:以迪马C18为色谱柱.甲醇-水(10:90)为流动相,检测波长252nm。结果:更昔洛韦在2.5~40mg·L^-1浓度范围内线性关系良好(r=0.9998),平均回收率为100.5%,RSD为0.21%。结论:本方法简便、快速、灵敏,可作为该制刺的质量控制。

关 键 词:更昔洛韦  高效液相色谱法  含量

Determination of ganciclovir Gel by HPLC
WANG Hai-ying.Determination of ganciclovir Gel by HPLC[J].Heilongjiang Medicine and Pharmacy,2009,32(3):26-26.
Authors:WANG Hai-ying
Institution:Department of Pharmacy of the Daqing Second Hospital;Daqing 163461;China
Abstract:Objective:To establish a HPLC method for Chromatographic column was DIKMA C~8,and the mobile determining the content of ganciclovir gel. Methods: phase was methanol--water (10:90). The UV detection wavelength was 254 nm. Results:There was a good linear relationship at the concentration range of 2.5 -40 mg·L^-1 in ganciclovir gel (r=0. 9998). The average recovery of ganciclovir was 100.5% ,and RSD was 0.21%. Conclusion : This method is simple ,rapid and accurate.
Keywords:ganciclovir  HPLC  content  
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