Antinociceptive effect of Teucrium polium leaf extract in the diabetic rat formalin test |
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Authors: | Baluchnejadmojarad Tourandokht Roghani Mehrdad Roghani-Dehkordi Farshad |
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Affiliation: | Department of Physiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. |
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Abstract: | This study was designed to evaluate the analgesic effect of Teucrium polium leaf extract in the diabetic rat formalin test. For this purpose, streptozotocin (STZ)-diabetic rats received intraperitoneal injection of this extract (100 and 200 mg/kg per day) for a period of 2 weeks. It was found out that Teucrium polium-treated diabetic rats exhibited a lower nociceptive score as compared to untreated diabetics. The results may suggest therapeutic potential of Teucrium polium extract for the treatment of diabetic hyperalgesia. |
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