| 血清前白蛋白、视黄醇结合蛋白和总胆汁酸在肝硬化分级诊断中的意义 |
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| 引用本文： | 袁立新,陈忠. 血清前白蛋白、视黄醇结合蛋白和总胆汁酸在肝硬化分级诊断中的意义[J]. 天津医药, 2011, 39(5): 424-425. DOI: 10.3969/j.issn.0253-9896.2011.05.012 |
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| 作者姓名： | 袁立新 陈忠 |
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| 作者单位： | 1. 江苏省丹阳市人民医院检验科2. 江苏省丹阳市人民医院 |
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| 摘 要： | 探讨血清前白蛋白（PA）、视黄醇结合蛋白（RBP）和总胆汁酸（TBA）在肝硬化Child-Pugh分级中的的作用。120例肝硬化患者按Child-Pugh分级标准分为三组：A组(A级，40例); B组(B级，42例); C组(C级，38例)。另设正常对照组40例。采用自动生化分析仪分别测定血清PA、RBP和TBA的含量。 肝硬化患者血清中PA和RBP含量较对照组均减低（P＜0.01或P＜0.05），且随着Child-Pugh积分升高而递减,各组间比较差异均有统计学意义(P＜0.01或P＜0.05)；而TBA较对照组明显升高, 且随着Child-Pugh积分升高而递增, 各组间比较差异有统计学意义(p＜0.01或＜0.05)。联合检测PA、RBP和TBA可以较好地判断肝硬化患者分级状况,对患者的治疗及预后提供一定的临床价值。
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| 关 键 词： | 肝硬化 前白蛋白 视黄醇结合蛋白 总胆汁酸 |
| 收稿时间： | 2010-07-15 |
| 修稿时间： | 2010-10-26 |
Significance of Prealbumin,Retinol Binding Protein and Total Bile Acid on Hepatic Cirrhosis Classification |
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| YUAN Lixin,CHEN Zhong. Significance of Prealbumin,Retinol Binding Protein and Total Bile Acid on Hepatic Cirrhosis Classification[J]. Tianjin Medical Journal, 2011, 39(5): 424-425. DOI: 10.3969/j.issn.0253-9896.2011.05.012 |
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| Authors: | YUAN Lixin CHEN Zhong |
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| Affiliation: | YUAN Lixin,CHEN Zhong Danyang People's Hospital,Jiangsu 212300,China |
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| Abstract: | Objective:To investigate the role of prealbumin(PA),retinol binding protein(RBP) and total bile acid(TBA) in Child-Pugh classification of hepatic cirrhosis.Methods:One hundred and twenty patients with hepatic cirrhosis were enrolled and divided into three groups according to Child-Pugh standard,A group(A grade,40 cases),B group(B grade,42 cases) and C group(C grade,38 cases),respectively.And 40 healthy cases were as normal control.Automatic biochemistry analysator was used to assay serum PA,RBP and TBA.Resu... |
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| Keywords: | liver cirrhosis prealbumin retinol-binding proteins plasma bile acids and salts prognosis |
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