| 白细胞介素—13对肾小球系膜细胞增殖的影响 |
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| 引用本文： | 蔡康荣,蔡春,揭新明.白细胞介素—13对肾小球系膜细胞增殖的影响[J].广西医学,2003,25(12):2384-2386. |
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| 作者姓名： | 蔡康荣 蔡春 揭新明 |
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| 作者单位： | 广东省湛江市广东医学院分析中心,524023 |
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| 摘 要： | 目的 :观察白细胞介素 - 1 3(IL - 1 3)对肾小球系膜细胞增殖的影响。方法 :应用流式细胞仪检测加入不同浓度 IL - 1 3作用后对肾小球系膜细胞 DNA含量的变化。结果 :各实验组的 DNA合成前期 (G1期 )细胞数增加 ,而合成期 (S期 )细胞数降低 ,各实验组与对照组比较 ,差异均有显著性 (P<0 .0 1 )。结论 :IL - 1 3具有抑制肾小球系膜细胞增殖作用
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| 关 键 词： | 白细胞介素—13 肾小球系膜细胞增殖 流式细胞仪 细胞周期 |
Effects of interleukin-13 on the cell cycle in glomerular mesangial cell |
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| Cai Kangrong,Cai Chun,Jie Xinming Analytic Center of Guangdong Medical College,Zhanjiang,Guangdong.Effects of interleukin-13 on the cell cycle in glomerular mesangial cell[J].Guangxi Medical Journal,2003,25(12):2384-2386. |
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| Authors: | Cai Kangrong Cai Chun Jie Xinming Analytic Center of Guangdong Medical College Zhanjiang Guangdong |
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| Institution: | Zhanjiang 524023 |
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| Abstract: | Objective:To observe the effect of interleukin 13 on the cell cycle in glomerular mesangial cell Methods:Flow cytometry was used to detect DNA content of glomerular mesangial cell in different concentration IL 13 Results:Compared with control group,DNA contents in each experiment groups increased in G1 phase and decreased in S phase,there were significantly different(P<0 01) Conclusion:IL 13 inhibits glomerular mesangial cell proliferation |
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| Keywords: | Glomerular mesangial cell Interleukin 13 Flow cytometry Cell cycle |
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