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声触诊组织量化技术诊断早期肝硬化的临床价值
引用本文:朱先存,张纯林,左鲁生,罗福成.声触诊组织量化技术诊断早期肝硬化的临床价值[J].东南国防医药,2012,14(6):511-513.
作者姓名:朱先存  张纯林  左鲁生  罗福成
作者单位:1. 解放军123医院特诊科,安徽蚌埠,233015
2. 解放军105医院特诊科,安徽合肥,230031
摘    要:目的探讨声触诊组织量化(virtual touch tissue quantification,VTQ)技术在早期肝硬化诊断中的价值。方法利用VTQ技术对185例受检者(对照组65例、慢性肝炎组68例、早期肝硬化组52例)肝脏右叶进行检查,测得靶区肝脏VTQ值。结果三组肝脏VTQ值差异有统计学意义(P〈0.01);以VTQ技术区分慢性肝炎组和早期肝硬化组的cut-off值为1.84 m/s,诊断早期肝硬化的敏感性为94.5%,特异性为84.5%。结论 VTQ技术能够定量反映肝组织硬度信息,对诊断早期肝硬化有重要的价值。

关 键 词:肝纤维化  早期肝硬化  声脉冲辐射力成像  声触诊组织量化技术  诊断

The clinic value of virtual touch tissue quantification technique in diagnosis of early liver cirrhosis
ZHU Xian-cun , ZHANG Chun-lin , ZUO Lu-sheng , LUO Fu-cheng.The clinic value of virtual touch tissue quantification technique in diagnosis of early liver cirrhosis[J].Journal of Southeast China National Defence Medical Science,2012,14(6):511-513.
Authors:ZHU Xian-cun  ZHANG Chun-lin  ZUO Lu-sheng  LUO Fu-cheng
Institution:1.Department of Special Diagnosis,123 Hospital of PLA,Bengbu,Anhui 233015,China;2.Department of Special Diagnosis,105 Hospital of PLA,Hefei,Anhui 230031,China
Abstract:Objective To explore the application of virtual touch tissue quantification (VTQ) technique in diagnosis of early liver cirrhosis. Methods The right lobes of liver in 185 patients in three groups (65 were healthy controls, 68 were patients with chronic hepatitis and 52 were patients with early liver cirrhosis ) were checked by VTQ technique. Results The VTQ values were significantly different in three groups (P 〈 0. 01 ). The VTQ value of 1.84 m/s was used as cut-off value to distinguish between chronic hepatitis B and early liver cirrhosis. The sensitivity for diagnosis of early liver cirrhosis was 94.5% and its specificity was 84. 5%. Conclusion VTQ technique could quantitatively reflect liver tissue stiffness information, and had im- portant value to diagnose early liver cirrhosis.
Keywords:liver fibrosis  early liver cirrhosis  acoustic radiation force impulse  virtual touch quantification technique  diagnosis
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