| 克雷伯氏菌暴发感染和实验研究 |
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| 引用本文： | 阮良,徐秀华,熊宏恩,纪标,李洁. 克雷伯氏菌暴发感染和实验研究[J]. 中南大学学报(医学版), 1996, 0(1) |
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| 作者姓名： | 阮良 徐秀华 熊宏恩 纪标 李洁 |
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| 作者单位： | 湘雅医院医院感染科 |
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| 摘 要： | 对某产婴室暴发医源性肺炎克雷伯氏菌感染作一调查，发现新生儿感染率达２１．６７％；以脐炎，结膜炎为主，２例死于败血症。收集自产婴室和其他病室的５６株菌的耐药谱分７型，５种噬菌体将５６株菌分成１２型，流行株和散发株间型别有显著性差异。质粒分型在３６种以上；流行株含２种质粒，酶切图谱近似，系同源株。
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| 关 键 词： | 克雷伯氏肺炎杆菌；新生儿室；医院；流行病学；细菌分型技术；抗药性，微生物；噬菌体；质粒 |
CLINICAL AND LABORATORY STUDIES OF THE OUTBREAK OF KLEBSIELLA PNEUMONIAE INFECTION |
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| Ruan Liang, Xu Xiuhua,Xiong Hong-en,Ji Biao, Li Jie. CLINICAL AND LABORATORY STUDIES OF THE OUTBREAK OF KLEBSIELLA PNEUMONIAE INFECTION[J]. Journal of Central South University. Medical sciences, 1996, 0(1) |
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| Authors: | Ruan Liang Xu Xiuhua Xiong Hong-en Ji Biao Li Jie |
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| Abstract: | rom September to October in l990,an outbreak of Klebsiella pneumoniae infection occurredin the Neonatal Unit of Obstetrical Department in our hospital.The morbidity rate was 2l.67%. Omphalitis and conjunctivitis were the main clinical manifestations. Two neonates died of sep-ticemia. The 56 strains which resisted to l6 antibiotics were classified into 7 types;these strainswere again divided into l2 types by 5 phages of KP. There was significant difference in types be-tween epidemic and sporadic strains,The isolation rate of plasmid was 85.7l%and more than 36types were discovered.Epidemic strains containing 2 plasmids with similar enzymatic-cleavagefingerprintings were considered as hOmologous strains. |
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| Keywords: | Klebsiella pneumoniae nurseries hospital epidemiology bacterial typing techniques drug resistance microbial bacteriophage plasmids |
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