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Non-coplanar polychlorinated biphenyls (PCBs) are direct agonists for the human pregnane-X receptor and constitutive androstane receptor, and activate target gene expression in a tissue-specific manner
Authors:Al-Salman Fadheela  Plant Nick
Institution:
  • Centre for Toxicology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, UK
  • Abstract:
    Keywords:AhR  Aryl hydrocarbon receptor  CAR  constitutive androstane receptor  PCB  polychlorinated biphenyls  PXR  pregnane‐X receptor
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