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低分子肝素与地尔硫Zhuo联合治疗不稳定型心绞痛的效果
引用本文:马立学,刘享亨,何世磊.低分子肝素与地尔硫Zhuo联合治疗不稳定型心绞痛的效果[J].齐鲁医学杂志,2001,16(1):18-20.
作者姓名:马立学  刘享亨  何世磊
作者单位:1. 青岛市第八人民医院心内科
2. 青岛海员医院
摘    要:①目的观察低分子肝素与地尔硫联合治疗不稳定型心绞痛的效果.②方法将58例不稳定型心绞痛病人随机分为两组,对照组27例用常规方法治疗,观察组31例加用低分子肝素、地尔硫.③结果与对照组比较,观察组临床症状明显改善(u=2.49,P<0.05),总有效率差异有显著性(X2=4.59,P<0.05);两组心电图ST-T段改善总有效率差异有显著性(X2=4.18,P<0.05).观察组出现咯血1例,停药后自行缓解,对照组未发现出血病人.④结论低分子肝素与地尔硫联合治疗不稳定型心绞痛效果较好.

关 键 词:不稳定型心绞痛  低分子量肝素  地尔硫Zhuo  联合药物治疗
文章编号:1008-0341(2001)01-0018-03
修稿时间:2000年2月26日

The efficacy of low molecular weight heparin and diltiazem in the treatment of unstable angina pectoris
MA Lixue,LIU Xiangheng,HE Shilei.The efficacy of low molecular weight heparin and diltiazem in the treatment of unstable angina pectoris[J].Medical Journal of Qilu,2001,16(1):18-20.
Authors:MA Lixue  LIU Xiangheng  HE Shilei
Institution:MA Lixue,LIU Xiangheng,HE Shilei Department of Cardiology,Qingdao No. 8 People's Hospital,Qingdao 266100
Abstract:Objective To investigate the efficacy of low molecular weight heparin (LMWH) and diltiazem in the treatment of unstable angina pectoris (UAP). Methods 58 patients with UAP were divided into 2 groups. The UAP subject group consisted of 31 patients, receiving LMWH, diltiazem and conventional therapy, including glucose-insulin-potassium (GIK), aspirin, betaloc, nitroglycerin and vitamin E, while the other 27 patients served as controls, receiving conventional therapy only. Results The efficacy of the therapy of LMWH and diltiazem was better than that of the control in terms of the clinical manifestations (u= 2. 59, P<0.05), the total efficacy was significant (X2 = 4.59 p<0.05 ). The total efficacy of ST-T changes in electrocardiogram was also significant (X2=4, 18, p<0.05). Conclusion LMWH and diltiazem therapy is effective for patients with UAP.
Keywords:angina  unstable  heparin  low molecular weight  diltiazem
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