高通量血液透析对维持性血液透析患者钙磷代谢的影响分析

目的探究高通量血液透析对维持性血液透析(MHD)患者钙磷代谢的影响。方法84例MHD患者作为研究对象,依据双色球法分为研究组与对照组,各42例。对照组给予低通量血液透析,研究组给予高通量血液透析。比较两组透析前、透析6个月后的钙磷代谢情况。结果透析6个月后,研究组甲状旁腺激素(261.33±25.21)pg/L、钙磷乘积(34.64±3.12)mg²/dl²、血磷(1.56±0.20)mmol/L、血钙(2.11±0.55)mmol/L,均优于对照组的(398.37±27.63)pg/L、(47.23±4.24)mg²/dl²、(1.81±0.31)mmol/L、(1.79±0.62)mmol/L,差异有统计学意义(P<0.05)。结论MHD患者在血液透析过程中使用高通量血液透析,可有效改善患者钙磷代谢水平,利于患者疾病治疗,值得在患者血液透析过程中推广使用。

Effect analysis of high-flux hemodialysis on calcium and phosphorus metabolism in patients with maintenance hemodialysis

Objective To investigate the effect of high-flux hemodialysis on calcium and phosphorus metabolism in patients with maintenance hemodialysis(MHD).Methods A total of 84 patients with MHD as study subjects were divided into research group and control group according to the two-color ball method,with 42 cases in each group.The control group received low-flux hemodialysis,and the research group received high-flux hemodialysis.The calcium and phosphorus metabolism before and 6 months after dialysis were compared between the two groups.Results After 6 months of dialysis,the parathyroid hormone(261.33±25.21)pg/L,calcium-phosphorus product(34.64±3.12)mg²/dl²,blood phosphorus(1.56±0.20)mmol/L,blood calcium(2.11±0.55)mmol/L of the research group were better than(398.37±27.63)pg/L,(47.23±4.24)mg²/dl²,(1.81±0.31)mmol/L,(1.79±0.62)mmol/L of the control group,and the difference was statistically significant(P<0.05).Conclusion The use of high-flux hemodialysis in MHD patients can effectively improve the calcium and phosphorus metabolism and facilitate patients’disease treatment,which is worthy of promotion and application.