激素联合枸橼酸氯米芬治疗内分泌失调不孕症的效果

目的 分析激素联合枸橼酸氯米芬治疗内分泌失调不孕症的效果.方法 84例内分泌失调不孕症患者,采取随机盲选法将其分为对照组及观察组,各42例.对照组患者实施常规治疗,观察组患者实施激素联合枸橼酸氯米芬治疗.对比两组临床疗效,治疗前后的性激素指标水平,排卵及妊娠情况.结果 观察组总有效率92.86％高于对照组的73.81％...

Effect of hormone combined with clomiphene citrate in the treatment of endocrine disorders and infertility

Objective To analyze the effect of hormone combined with clomiphene citrate in the treatment of endocrine disorders and infertility.Methods A total of 84 patients with endocrine disorders and infertility were randomly selected and divided into control group and observation group,with 42 cases in each group.Patients in the control group was treated with conventional therapy,and patients in the observation group was treated with hormone and clomiphene citrate.The clinical efficacy,sex hormones levels before and after treatment,ovulation and pregnancy status were compared between the two groups.Results The total effective rate 92.86%of the observation group was higher than 73.81%of the control group,and the difference was statistically significant(P<0.05).After 1 cycle of treatment,the follicle stimulating hormone(11.85±2.51)mIU/ml and luteinizing hormone(6.38±1.58)mIU/ml of the observation group were higher than(8.76±2.35)and(4.06±1.24)mIU/ml of the control group,and the difference was statistically significant(P<0.05).In the control group,the ovulation rates were 26.19%(11/42),50.00%(21/42)and 73.81%(31/42),and pregnancy rates were 9.52%(4/42),19.05%(8/42)and 38.10%(16/42)at 1,2 and 3 cycles of treatment;in the observation group,the ovulation rates were 69.05%(29/42),78.57%(33/42)and 92.86%(39/42),and the pregnancy rates were 26.19%(11/42),42.86%(18/42)and 64.29%(27/42)at 1,2 and 3 cycles of treatment.The ovulation rate and pregnancy rate in the observation group were higher than those in the control group at 1,2 and 3 cycles of treatment,and the difference was statistically significant(P<0.05).Conclusion Hormone combined with clomiphene citrate has significant effect on patients with endocrine disorder and infertility,and is worth adopting and using.