| 喹硫平对脑电图的影响 |
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| 引用本文： | 李晓一. 喹硫平对脑电图的影响[J]. 浙江医学, 2008, 30(3): 216-217 |
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| 作者姓名： | 李晓一 |
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| 作者单位： | 浙江省立同德医院省精神卫生研究院,杭州,310012 |
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| 摘 要： | 目的观察新的非典型抗精神病药喹硫平（quetiapine）对脑电图的影响。方法开放性收集门诊和住院诊断为分裂样精神障碍及精神分裂症的首诊患者98例，男性65例，女性33例，在喹硫平治疗前和治疗8周后进行脑电描记术（electroencephalogaphy，EEG）描记检查；疗效评定用简明精神病量表（BPRS）。结果喹硫平治疗分裂样精神障碍（21例）及精神分裂症（77例）疗效肯定，脑电图异常发生率为27％，多以轻度异常5～7C／Se活动散在各导为主，未发现有痫样活动。临床也未见患者有抽搐发作。结论喹硫平治疗后脑电图异常变化有一定的发生率但异常的程度低。
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| 关 键 词： | 喹硫平 EEG 分裂样精神障碍 精神分裂症 喹硫平 脑电图 影响 schizophrenia treatment electroencephalography quetiapine 程度 异常发生率 异常变化 抽搐发作 首诊患者 临床 痫样活动 发现 轻度 疗效肯定 结果 BPRS 简明精神病量表 |
| 修稿时间： | 2007-09-10 |
The effect of quetiapine on electroencephalography in treatment of schizophrenia |
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| LI Xiaoyi. The effect of quetiapine on electroencephalography in treatment of schizophrenia[J]. Zhejiang Medical Journal, 2008, 30(3): 216-217 |
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| Authors: | LI Xiaoyi |
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| Affiliation: | LI Xiaoyi. Zhejiang Tongde Hospital,Hangzhou 300012,China |
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| Abstract: | Objective To investigate the effect of atypical antipsychotics quetiapine on electroencephalography (EEG) in treatment of schizophrenia. Methods Ninety eight patients (male 65,female33) diagnosed as schizophrenia (77 cases) and schizophrenia-like state (21 cases) received monotherapy with quetiapine. Digital EEG were performed before and 8w after treatment; the BPRS was used to assess the efficacy of treatment. Results The abnormality rate of EEG was 27% after quetiapine treatment,but all in mild types. The... |
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| Keywords: | Quetiapine EEG Schizophrenia-like state Schizophrenia |
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