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氩氦刀冷冻治疗原发性肝癌的初步临床研究
引用本文:周霖,杨永平,冯永毅,陆荫英,王春平,王新真,安林静,张昕,王福生. 氩氦刀冷冻治疗原发性肝癌的初步临床研究[J]. 癌症, 2009, 28(1): 58-62
作者姓名:周霖  杨永平  冯永毅  陆荫英  王春平  王新真  安林静  张昕  王福生
作者单位:军医进修学院,北京,100853;解放军第302医院肝癌治疗研究中心,北京,100039;解放军第302医院肝癌治疗研究中心北京,100039
摘    要:背景与目的:近年来氩氦刀冷冻治疗肝癌发展迅速,本研究旨在通过回顾性分析,评价氩氦刀冷冻治疗无法手术切除的原发性肝癌的临床疗效。方法:选择124例经氩氦刀冷冻治疗的原发性肝癌患者.根据巴塞罗那分期分成早期、中期及进展期肝癌组,以治疗后患者的临床表现、局部病灶CT变化、AFP下降情况、术后并发症的发生及平均生存时间作为评价指标。结果:氩氦刀冷冻治疗肝癌后患者的并发症少,82.6%的患者术后AFP降低,92.3%的肿瘤缩小或保持不变。截止至2008年4月.仍有14例患者生存.110例患者死亡。早期、中期及进展期肝癌组的中位生存时间分别为31.25个月、17.41个月、6.82个月。结论:对于无法切除的中晚期肝癌,氩氦刀治疗的并发症少.有一定的疗效。

关 键 词:原发性肝癌  冷冻治疗  疗效  并发症  生存期

Efficacy of argon-helium cryosurgical ablation on primary hepatocellular carcinoma: a pilot clinical study
Lin Zhou,, Yong-Ping Yang, Yong-Yi Feng, Yin-Ying Lu, Chun-Ping Wang, Xin-Zhen Wang, Lin-Jing An, Xin Zhang , Fu-Sheng Wang. PLA Postgraduate Medical School,Beijing,,P. R. China . Liver Carcinoma Therapy Research Center PLA Hospital,,P. R. China. Efficacy of argon-helium cryosurgical ablation on primary hepatocellular carcinoma: a pilot clinical study[J]. Chinese journal of cancer, 2009, 28(1): 58-62
Authors:Lin Zhou     Yong-Ping Yang   Yong-Yi Feng   Yin-Ying Lu   Chun-Ping Wang   Xin-Zhen Wang   Lin-Jing An   Xin Zhang    Fu-Sheng Wang. PLA Postgraduate Medical School  Beijing    P. R. China . Liver Carcinoma Therapy Research Center PLA Hospital    P. R. China
Affiliation:Lin Zhou,1,2 Yong-Ping Yang,2 Yong-Yi Feng,2 Yin-Ying Lu,2 Chun-Ping Wang,2 Xin-Zhen Wang,2 Lin-Jing An,2 Xin Zhang2 , Fu-Sheng Wang21. PLA Postgraduate Medical School,Beijing,100853,P. R. China 2. Liver Carcinoma Therapy Research Center PLA 302 Hospital,100039,P. R. China
Abstract:Background and Objective: Recent years, great progression has been made in treating primary hepatocellular carcinoma (HCC) with argon- helium cryosurgical ablation. This study was to evaluate its efficacy on unresectable primary HCC. Methods: A total of 124 primary HCC patients were divided into early stage, middle stage and advanced stage groups according to BCLC staging classification. Clinical symptoms, tumor size, serum level of alpha-fetoprotein (AFP), complications, and survival time were analyzed. Re...
Keywords:liver neoplasm  cryosurgery  efficacy  complication  survival  
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