| 用NIH3T3细胞转化试验对松花江江水潜在致癌性的研究 |
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| 引用本文： | 刘家仁 张尤恩. 用NIH3T3细胞转化试验对松花江江水潜在致癌性的研究[J]. 环境与健康杂志, 1998, 15(5): 203-205 |
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| 作者姓名： | 刘家仁 张尤恩 |
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| 作者单位： | 哈尔宾医科大学公共卫生学院，加拿大卡尔加里大学医学院公共卫生系 |
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| 摘 要： | 为探讨松花江江水潜在致癌性，检测了哈尔滨市上游１５ｋｍ处江水对ＮＩＨ３ＴＨ３细胞的恶性转化作用。试验结果表明：乙醚提取各剂量均对细胞有一定毒性，能诱发典型的细胞转化灶，其转化率呈现剂量－效应关系。提示，该江水具有潜在致癌作用。
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| 关 键 词： | NIH3T3细胞 致癌性 松花江 水质评价 转化试验 |
Carcinogenecity Research on Water of Songhua River with NIH3T3 Cell Transformation Test |
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| Liu Jiaren,Zhang Youen,Pang Yongxun,et al The Public Health College of Harbin Medical University. Carcinogenecity Research on Water of Songhua River with NIH3T3 Cell Transformation Test[J]. Journal of Environment and Health, 1998, 15(5): 203-205 |
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| Authors: | Liu Jiaren Zhang Youen Pang Yongxun et al The Public Health College of Harbin Medical University |
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| Affiliation: | Liu Jiaren,Zhang Youen,Pang Yongxun,et al The Public Health College of Harbin Medical University,150001 |
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| Abstract: | To explore the potential carcinogenecity of water of Songhua River,the malignant transformation of NHI3T3 cells was detected by the water samples,which were collected in the upper reaches of Songhua River 15 km far from Harbin The result showed that the ether extract of water sample had certain toxicity to the tested cells could induce typical malignant transformatd foci,and transformation rates presented a dose effect relationship It indicated that the Songhua River had potential carcinogenecity |
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| Keywords: | Ether extract NIH3T3 cells Carcinogenecity |
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