| 不同低氧环境对大鼠肺动脉平滑肌细胞增殖的影响 |
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| 引用本文： | 张昱,张伟.不同低氧环境对大鼠肺动脉平滑肌细胞增殖的影响[J].青海医学院学报,2011,32(1):21-24. |
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| 作者姓名： | 张昱 张伟 |
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| 作者单位： | 青海大学医学院生物学教研室 |
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| 基金项目： | 教育部"春晖计划"科技项目，青海大学医学院青年科研项目 |
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| 摘 要： | 目的 探讨不同低氧环境对大鼠肺动脉平滑肌细胞(pulmonary arterial smooth muscle cells,PASMCs)增殖活性的影响.方法 将原代培养的大鼠PASMCs分为常氧组(21% O2,5% CO2)、低氧组(10% O2,85% N2,5% CO2)、缺氧组(1% O2,94% N2,5%...
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| 关 键 词： | 缺氧 肺动脉平滑肌细胞 增殖 影响 |
EFFECT OF DIFFERENT HYPOXIA ENVIRONMENT ON THE PROLIFERATION OF PULMONARY ARTERIAL SMOOTH MUSCLE CELLS IN RATS |
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| Zhang Yu,Zhang Wei.EFFECT OF DIFFERENT HYPOXIA ENVIRONMENT ON THE PROLIFERATION OF PULMONARY ARTERIAL SMOOTH MUSCLE CELLS IN RATS[J].Journal of Qinghai Medical College,2011,32(1):21-24. |
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| Authors: | Zhang Yu Zhang Wei |
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| Institution: | Zhang Yu,Zhang Wei(Department of Biology,Qinghai University Medical College) |
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| Abstract: | Objective To explore the effect on different hypoxic proliferation of rat pulmonary arterial smooth muscle cells(PASMCs).Methods The primary culture PASMCs of rat were randomly divided into three groups,including: normoxia group(21 % O2,5 % CO2),hypoxia group(10 % O2,85 % N2,5 % CO2)and anoxia group(1 % O2,94 % N2,5 % CO2).The proliferation was tested by cell count and methyl thiazolyl tetrazolium(MTT) method.Results The PASMCs count of anoxia group was more than normoxia group and hypoxia group after 2 day... |
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| Keywords: | Anoxia Pulmonary smooth muscle cells Proliferation Hypoxic pulmonary hypertension |
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