百合固金汤治疗慢性阻塞性肺疾病稳定期50例

目的:研究百合固金汤对慢性阻塞性肺疾病(COPD)稳定期患者的临床疗效.方法:100例COPD稳定期(肺阴亏虚型)患者随机分为观察组和对照组各50例.对照组采用西医COPD稳定期常规疗法,观察组服用百合固金汤治疗.观察两组肺阴亏虚证候积分、生活质量、肺功能.结果:观察组总有效率为90.0％优于对照组的74.0％(P＜0.05)；治疗后观察组呼吸症状、活动能力及疾病影响3个维度和st.Georges呼吸问卷调查(SGRQ)总评分均低于对照组(P＜0.05)；治疗后两组一秒用力呼气容积(FEV1)均较治疗前明显上升,观察组上升更明显(P＜0.05)；治疗后观察组FEV1/用力肺活量(FVC)较对照组高(P＜0.05)；治疗后观察组肺阴亏虚积分明显低于对照组(P＜0.05).结论:百合固金汤能改善COPD稳定期肺阴亏虚型患者证候,改善临床症状和肺功能,提高患者生活质量.

Clinical Research on Baihe Gujin Decoction for Treating 50 Cases in Stabilization Period of Chronic Obstructive Pulmonary Disease

Objective: To investigate the clinical effect of Baihe Gujin decoction for treating stabilization period of chronic obstructive pulmonary disease (COPD). Method: One hundred cases in stable period of COPD by diagnostic criteria, with the lung yin deficiency syndrome, were randomly divided into treatment group and control group (n=50 each). The control group was treated with western medicine, and the treatment group was treated with routine therapy and Baihe Gujin decoction. The clinical symptoms, signs, symptoms and pulmonary function in the two groups were observed before and after treatment. Result: In observation group, the total efficiency of 90% was better than 74% of control group (P<0.05). After treatment, the respiratory symptoms and diseases affecting the activities of 3 dimensions and total score of St George's respiratory questionnaire (SGRQ) in the treatment group were lower than those in the control group (P<0.05). After treatment in the two groups, the forced expiratory volume in one second (FEV₁) was significantly increased, the treatment group increased more obvious (P<0.05). After treatment FEV₁/forced vital capacity (FVC) in the treatment group was higher than that in the control group (P<0.05). After treatment lung yin deficiency score in the treatment group was significantly lower than that in the control group (P<0.05). Conclusion: Baihe Gujin decoction could improve the stable stage of COPD with lung yin deficiency syndromes, improve the clinical symptoms and lung function, improve patients' quality of life.