| 运动对大鼠胸主动脉内皮素和一氧化氮合成酶的影响 |
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| 引用本文： | 殷松楼,张宝慧. 运动对大鼠胸主动脉内皮素和一氧化氮合成酶的影响[J]. 中国运动医学杂志, 1998, 17(1): 8 |
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| 作者姓名： | 殷松楼 张宝慧 |
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| 作者单位： | 徐州医学院附属医院，北京医科大学运动医学研究所 |
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| 基金项目： | 国家体委重点科研项目基金 |
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| 摘 要： | 雄性Ｗｉｓｔａｒ大鼠随机分成两组：对照组和运动组，游泳运动４周（１５小时／天，５天／周）后，测定大鼠胸主动脉和血浆内皮素（ＥＴ）含量及一氧化氮合成酶（ＮＯＳ）活性，结果表明运动组主动脉和血浆ＥＴ含量较对照组明显下降（Ｐ＜０．０５），运动组主动脉ＮＯＳ活性较对照组明显增强，结果提示运动对１Ｄ和ＮＯＳ的影响在血管系统对运动适应及运动防治心血管疾病中有重要的意义。
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| 关 键 词： | 运动，大鼠胸主动脉，内皮素，一氧化氮合成酶 |
Effect of Exercise on Endothelin and nitric Oxide Synthesis of Thoracic Aorta in Rat |
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| Abstract: | Male Wistar rats were randomly divided into two groups: the control guoup (GG) and the swimming group (SG)(Swimming exercise 1.5 hours a day.5 days a week for four weeks).Serum and thoracic aorta levels of endothelin(ET) -and activity of nitric oxide synthesis (NOS) were measured the results showed that the serum and thoracic and thoracic.aorta levels of ET in SG were significantly decreased compared with that in.GG(p <0.05)and the activity of NOS in SG was evidently enhanced.the. results that exercise played an important role in adaptation of vascular of vascular system and prevention and treatment of cardiovascular diseases. |
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| Keywords: | Key Words:exercise thoracic aorta endothelin nitric oxide synthesis |
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