振动对小鼠体内磺胺嘧啶（SD）分布的影响

为了研究振动对生物体内物质的耗散作用，本文用药代动力学的方法在振动频率为２０Ｈｚ，加速度为１．１ｇ与５０Ｈｚ，４．４ｇ的条件下分别测试了小鼠体内血、肝与肾组织中磺胺啮咬（ＳＤ）在１至９小时内的分布，结果表明：２０Ｈｚ实验组血中ＳＤ浓度峰伍比对照组提前３小时，在振动１小时时，小鼠体内血、肝与肾组织中ＳＤ含量均比对照组高，但振动３小时至９小时内，其含量均比对照组低，从管道气栓体外模拟实验与本文的研究可得到启示：在上述频率与强度条件下，振动对生物体可能有促进血液循环的作用。

EFFECTS OF THE VIBRATION ON THE DISTRIBUTION OF SD IN MICE

In order to understand the effects of vibration on the material dissipation in the organism, the dis-tribution of SD in mice was observed by the method of the pharmacokinetics,Awhole-body vibration at the fre-quency of 20Hz or 50Hz was applied to 84 mice for 1-9hours.the vibration produced changes of the distributionof SD in mice: For the blood peak of SD in mice,the experin1ent group at 20Hz was 3 hours earlier than the con-trol group.It also showed that for the concenration of SD in the blood,liver , kidney tissues, the experimentgroups by vibration exposure were higher than the control group at 1 hour,but they were lower from 3 hours to9hours. This indicates that the vibration may raise the blood velocity in the arterioles and the capillaries.