年轻子宫内膜癌的临床特点及预后分析

目的 探讨年轻子宫内膜癌的临床特点及预后.方法 对82例确诊的子宫内膜癌患者进行回顾性分析,其中≤45岁31例(年轻组),＞45岁51例(年老组),分析两组患者的临床特点、诊治情况及预后.结果 年轻组原发性不孕率和妊娠＜3次率38.7%(12/31)和74.2%(23/31)]明显高于年老组3.9%(2/51)和29.4%(15/51)](P＜0.05).两组患者肌层浸润程度比较,差异有统计学意义(P＜0.05);而病理类型、组织学分级、手术病理分期、5年生存率及复发时间比较,差异均无统计学意义(P＞0.05).结论 不孕或少孕为年轻子宫内膜癌的发病因素;年轻子宫内膜癌肌层浸润程度较年老患者轻,病理类型、组织学分级、手术病理分期与年老患者相似,但并没有获得比年老者更好的预后.

Abstract：

Objective To investigate the clinical characteristics and prognosis of young patients with endometrial cancer. Methods Eighty-two cases with endometrial cancer were analyzed retrospectively,31 cases in the young group were ≤ 45 years old, and 51 cases in the old group were ＞ 45 years old. The clinical characteristics, diagnosis, treatment and prognosis between the two groups were compared. Results Twelve cases with primary infertility took up 38.7% in the young group,23 cases with less than 3 times of pregnancy occupied 74.2%, and there was no statistical difference,compared with the old group 3.9%(2/51)and 29.4% (15/51)] (P＜0.05). There was statistically significant between the two groups in myometrial invasion (P ＜ 0.05 ); while there was no significance between the two groups in pathological type, histological grade,clinical stage, 5-year survival rate and recurrence period (P＞0.05). Conclusion Infertility or less pregnancy are risk factors for endometrial cancer in the young; the degree of endometrial invasion in the young is more shallow than that in the old; there is no significant difference between the young and the old in pathological type, histological grade and clinical stage; but the prognosis is similar between the young and the old patients.

Analysis of clinical characteristics and prognosis of young patients with endometrial cancer

Objective To investigate the clinical characteristics and prognosis of young patients with endometrial cancer. Methods Eighty-two cases with endometrial cancer were analyzed retrospectively,31 cases in the young group were ≤ 45 years old, and 51 cases in the old group were ＞ 45 years old. The clinical characteristics, diagnosis, treatment and prognosis between the two groups were compared. Results Twelve cases with primary infertility took up 38.7% in the young group,23 cases with less than 3 times of pregnancy occupied 74.2%, and there was no statistical difference,compared with the old group 3.9%(2/51)and 29.4% (15/51)] (P＜0.05). There was statistically significant between the two groups in myometrial invasion (P ＜ 0.05 ); while there was no significance between the two groups in pathological type, histological grade,clinical stage, 5-year survival rate and recurrence period (P＞0.05). Conclusion Infertility or less pregnancy are risk factors for endometrial cancer in the young; the degree of endometrial invasion in the young is more shallow than that in the old; there is no significant difference between the young and the old in pathological type, histological grade and clinical stage; but the prognosis is similar between the young and the old patients.