预存式自体输血在腰椎间盘突出手术中的应用疗效研究

目的 探讨预存式自体输血在腰椎间盘突出手术中应用的疗效.方法 采用分层抽样的方法将术中输血的50例腰椎间盘突出症患者随机分为两组,研究组(30例)采用预存式自体输血,对照组(20例)未进行预存式自体输血,将两组患者围手术期出血量、自体输血量及异体输血量、手术前后的血常规变化和输血后不良反应发生情况进行比较.结果 研究组围手术期出血量为(720±665)ml,低于对照组的(1060±558)ml,但差异无统计学意义(P＞0.05).研究组均未输注异体血而且安全渡过围手术期.两组术前、术后3 d、术后7 d血红蛋白水平、红细胞计数和白细胞计数比较差异均无统计学意义(P＞0.05),血小板计数在术后7 d两组比较差异有统计学意义(P＜0.05).研究组未见输血反应发生,对照组出现1例输血反应.结论 腰椎间盘突出手术中采用预存式自体输血可避免输注异体血,避免了异体输血的诸多不良反应,且临床疗效与输注异体血差异无统计学意义.

Abstract：

Objective To investigate the effect of predeposit autotransfusion in operation of the patients with lumbar disc protrusion.Methods Fifty patients of transfusion with lumbar disc protrusion were assigned into two groups by stratified sampling randomly,30 patients whose blood were predeposited before operation in experimental group,and the other 20 patients whose blood were not predeposited before operation in control group.The blood loss,the blood requirements during operations,the hemotological routine indexes and the complications related to blood transfusion were compared respectively.Results The blood loss of experimental group (720 ± 665 ) ml ] perioperative period was lower than that of control group ( 1060 ± 558 ) ml ],but there was no significant difference between two groups (P ＞ 0.05 ).All the patients in experimental group went through perioperative period safely without allogenic blood transfusion.Hemoglobin,red blood cell and white blood cell were not significantly different between two groups before and after operation for 3,7 days (P＞ 0.05 ),the platelet count after operation for 7 days was significantly different between two groups (P ＜ 0.05).No complication was observed in experimental group but 1 case with complication was observed in control group.Conclusions Predeposit autotransfusion is an effective to avoid homologous blood transfusion and its complications for the patients with lumbar disc protrusion.Furthermore,the clinical effect is not significantly different between the predeposit autotransfusion patients and the allogenic blood transfusion patients.

The study on the effect of predeposit autotransfusion in operation of lumbar disc protrusion

Objective To investigate the effect of predeposit autotransfusion in operation of the patients with lumbar disc protrusion.Methods Fifty patients of transfusion with lumbar disc protrusion were assigned into two groups by stratified sampling randomly,30 patients whose blood were predeposited before operation in experimental group,and the other 20 patients whose blood were not predeposited before operation in control group.The blood loss,the blood requirements during operations,the hemotological routine indexes and the complications related to blood transfusion were compared respectively.Results The blood loss of experimental group (720 ± 665 ) ml ] perioperative period was lower than that of control group ( 1060 ± 558 ) ml ],but there was no significant difference between two groups (P ＞ 0.05 ).All the patients in experimental group went through perioperative period safely without allogenic blood transfusion.Hemoglobin,red blood cell and white blood cell were not significantly different between two groups before and after operation for 3,7 days (P＞ 0.05 ),the platelet count after operation for 7 days was significantly different between two groups (P ＜ 0.05).No complication was observed in experimental group but 1 case with complication was observed in control group.Conclusions Predeposit autotransfusion is an effective to avoid homologous blood transfusion and its complications for the patients with lumbar disc protrusion.Furthermore,the clinical effect is not significantly different between the predeposit autotransfusion patients and the allogenic blood transfusion patients.