原发性骨淋巴瘤的影像学及临床病理特征

 原发性骨淋巴瘤（PLB）为非霍奇金淋巴瘤（NHL），是一类罕见的结外淋巴瘤，占所有NHL的1 %、结外淋巴瘤的5 %、原发于骨的恶性肿瘤的7 %。目前公认的PLB诊断标准为：肿瘤局限于单骨，临床和影像学检查未发现有其他系统病灶；病理组织学上确诊骨病灶为淋巴瘤；就诊时只有局部浸润，或至少在原发灶出现6个月后才有远处骨骼和其他部位的转移。由于PLB 表现的多样性和异质性，且发病率较低，导致诊断困难，现分析归纳其临床病理及影像学特征，以提高认识，降低误诊和漏诊率。

Imaging and clinicopathological characteristics of primary lymphoma of bone

Primary lymphoma of bone （PLB） refers to non-Hodgkin lymphoma （NHL）, which is an uncommon extranodal lymphoma, accounting for 1% of all NHL, 5 % of extranodal lymphoma and 7 % of primary bone tumor. Currently, the diagnostic criteria of PLB includes a.primary focus in a single bone; positive histological diagnosis; and no evidence of distant soft tissue or distant lymph node involvement. The diversity, hereditery, and lower incidence of PLB make it difficuh to diagnose. In order to decrease the rate of misdiagnosis and missed diagnosis,the clinical, pathological, and imaging characteristics of PLB in this study are analyzed.