经尿道电凝与膀胱灌注治疗放射性膀胱炎的临床对照研究

目的观察经尿道电凝术治疗放射性膀胱炎的疗效。方法对80例放射性膀胱炎患者平均分成两组：Ⅰ组采用经尿道电凝术治疗,Ⅱ组采用膀胱内灌注4%甲醛溶液治疗,术后进行随访观察疗效。结果患者随访3~44个月,平均（25±3）个月,Ⅰ组术后再出血率为2.50%,Ⅱ组术后再出血率为17.50%,差异有统计学意义（χ2=5.00,P〈0.05）;术后有严重尿频、尿急不良反应者Ⅰ组仅1例（2.5%）,Ⅱ组有6例（15.00%）,差异有统计学意义（χ2=3.91,P〈0.05）。结论经尿道电凝术治疗宫颈癌放疗后放射性膀胱炎疗效确切,不良反应少,是控制放射性膀胱炎膀胱内出血的一种有效方法。

Comparison of the efficacy of transurethral electrocoagulation and intravesical instillation in treating radiation cystisis

Objective To study the efficacy of transurethral electrocoagulation in treating radiation cystisis.Methods 80 patients were divided into two groups.Patients in Group I were treated with transurethral electrocoagulation.For patients in Group Ⅱ,4% formaldehyde was instilled into the bladder and remained for 20 minutes.Results During the follow-up of 3~44 months,rehaemorrhage rate was 2.50% and 17.50% in Group Ⅰand Group Ⅱ respectively,which had statistical significance（χ2=5.00,P0.05）.The adverse reaction rate was 2.50% and 15.00% in Group Ⅰand Group Ⅱ respectively,which had statistical significance（χ2=3.91,P0.05）.Conclusions Transurethral electrocoagulation is effective and safe in treating cystisis.