| 用生物素标记Y特异DNA探针进行产前性别诊断 |
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| 引用本文： | 董伟峰 赵丽. 用生物素标记Y特异DNA探针进行产前性别诊断[J]. 华西医科大学学报, 1990, 21(3): 277-280 |
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| 作者姓名： | 董伟峰 赵丽 |
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| 摘 要： |
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| 关 键 词： | 产前性别诊断 DNA探针 生物素标记 |
Prenatal sex identification with biotinylated human Y-specific DNA probe |
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| W Dong,S Jiang,S Zhang,L Zhao. Prenatal sex identification with biotinylated human Y-specific DNA probe[J]. Journal of West China University of Medical Sciences, 1990, 21(3): 277-280 |
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| Authors: | W Dong S Jiang S Zhang L Zhao |
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| Affiliation: | Department of Medical Genetics, Chengdu First Municipal Hospital. |
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| Abstract: | Using biotinylated human Y-specific DNA probe PHY2.1 and Cos 84, we carried out Southern and dot hybridization with human DNA from artificially aborted chorionic villi, and with DNA of peripheral lymphocytes from normal male and female. The results show that PHY2.1 may be applied in prenatal sex identification both by Southern and by dot hybridization but with Cos 84, only Southern hybridization could be used. |
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