| 吉林地区丙型肝炎病毒基因分型及临床意义的研究 |
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| 引用本文： | 李晓峰,马寅芙,杨广民.吉林地区丙型肝炎病毒基因分型及临床意义的研究[J].中国实用医药,2011,6(23):33-34. |
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| 作者姓名： | 李晓峰 马寅芙 杨广民 |
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| 作者单位： | 吉林省人民医院,长春,130021 |
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| 摘 要： | 目的了解吉林地区HCV基因分型情况,为HCV感染者的诊断和治疗提供重要的科学依据。方法荧光定量RT-PCR检测165例抗-HCV阳性血清标本,并对153例HCV-RNA阳性的血清标本应用基因芯片法进行HCV基因分型。结果 153例阳性标本中HCV1b型85例,HCV2a型63例,HCV1b/2a混合型5例。结论吉林地区HCV基因型主要为1b型,2a型次之,同时存在HCV1b/2a混合型。
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| 关 键 词： | 丙型肝炎病毒 荧光定量RT-PCR 基因分型 |
Genotyping and clinical significance of hepatitis C virus in Jilin |
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| LI Xiao-feng,MA Yin-fu,YANG Guang-min.Genotyping and clinical significance of hepatitis C virus in Jilin[J].China Practical Medical,2011,6(23):33-34. |
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| Authors: | LI Xiao-feng MA Yin-fu YANG Guang-min |
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| Institution: | LI Xiao-feng,MA Yin-fu,YANG Guang-min.People's Hospital of Jilin Province,Changchun 130021,China |
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| Abstract: | Objective To investigate the distribution of hepatitis C virus(HCV) genotypes in Changchun and to provide information for the diagnosis and treatment of HCV.Methods Eighty-nine samples HCV-RNA positive from 165 samples anti-HCV positive sera by fluorescence quantitative RT-PCR were further genotyped by gene chip.Results Forty-nine sera was type 1b,63 sera was type 2a and 3 sera was 1b/2a mixed-type among 153 samples with HCV-RNA positive.Conclusion HCVlb is the most dominant genotype,HCV2a is the second and... |
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| Keywords: | Hepatitis C virus Fluorescence quantitative RT-PCR Genotype |
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