中波高能紫外线最小红斑量值测定

目的探讨中波高能紫外线最小红斑量值(MED)范围及其与年龄、性别、皮肤日光反应类型的关系。方法以Dualight targeted Phototherapy System UV120-2的UVB作为照射光源,测定73名健康志愿者和35例白癜风患者腹部正常皮肤的MED值范围。结果108名受试者MED值为(189.17±56.156)mJ/cm2,范围为90～330mJ/cm2;Ⅲ型皮肤为(155.88±34.996)mJ/cm2(90～210mJ/cm2),Ⅳ型皮肤为(218.95±54.957)mJ/cm2(120～330mJ/cm2),Ⅲ型显著低于Ⅳ型(P<0.01)。男性受试者中,Ⅲ型为(154.29±39.443)mJ/cm2(90～210mJ/cm2),Ⅳ型为(224.4±54.854)mJ/cm2(150～330mJ/cm2),男性Ⅲ型显著低于Ⅳ型(P<0.01)。女性受试者中,Ⅲ型为(157±32.179)mJ/cm2(90～210mJ/cm2),Ⅳ型为(214.69±55.532)mJ/cm2(120～330mJ/cm2),女性Ⅲ型也显著低于Ⅳ型(P<0.01)。两性别组间和各年龄组间比较无统计学差异(P>0.05)。结论中波高能紫外线的MED值与性别和年龄无直接关系,皮肤日光反应类型是影响其重要因素。

Determination of UVB Minimal Erythema Dose of Normal Skin to Dualight Targeted Phototherapy System

Objective To investigate the minimal erythema dose (MED) of normal skin to UVB of Dualight targeted phototherapy system,and observe its relationship to sex,age,skin types to sunlight,etc.Methods 73 healthy volunteers and 35 patients with vitiligo were enrolled,whose normal skin was tested by UVB of Dualight targeted Phototherapy System UV120-2.Results The MED value was (189.17±56.156) mJ/cm2 (range:90～330 mJ/cm2)among all volunteers and patients.It was (155.88±34.996)mJ/cm2 (range:90～210mJ/cm2)in skin type Ⅲ,and (218.95±54.957)mJ/cm2 (range:120～330mJ/cm2) in skin type Ⅳ.The MED value in skin type Ⅲ was significantly lower than that in skin type Ⅳ(P<0.01).Among males,the MED value was (154.29±39.443)mJ/cm2(range:90～210mJ/cm2)in skin type Ⅲ,and(224.4±54.854)mJ/cm2(range:150～330mJ/cm2)in skin type Ⅳ.Among females,the MED value was(157±32.179)mJ/cm2(range:90～210mJ/cm2)in skin type Ⅲ,and(214.69±55.532)mJ/cm2(range:120～330mJ/cm2)in skin type Ⅳ.The MED value in skin type Ⅲ was significantly lower than that in skin type Ⅳ among both males and females(P<0.01).There was no difference of MED value between males and females,or among four age groups(P>0.05).Conclusions It is indicated that UVB-MED value of Dualight targeted Phototherapy System UV120-2 is mainly dependent on the skin types to sunlight,but it is not related to sex and age distributions.