孕期细菌性阴道病与不良妊娠结局关系的探讨

目的通过对孕妇进行细菌性阴道病(bacterial vaginosis,BV)筛查及治疗,探讨孕期BV与不良妊娠结局的关系。方法选取150例妊娠合并BV给予治疗的患者为A组;选取年龄、孕周与之匹配因故未治疗的81例妊娠合并BV的患者为B组;选取同期行围产监测的150例正常孕妇为C组,比较3组不良妊娠结局及宫内感染率。结果 B组中流产、早产、胎膜早破、产褥感染、新生儿窒息、新生儿感染的发生率均高于A、C组,差异有统计学意义(P﹤0.05)。结论孕期BV可导致不良妊娠结局,治疗后可降低宫内感染率,减少妊娠不良结局的发生。

Study on the relationship between bacterial vaginosis and adverse pregnancy outcomes

Objective To discusse the relationship between bacterial vaginosis（ BV） in pregnancy and adverse pregnancy outcomes through BV screening and treatment in pregnant women. Methods 150 cases of pregnant women with BV under treatment were selected into group A,81 cases with BV under no treatment matching with age and gestational weeks were selected into group B,150 normal pregnant women under perinatal monitoring over the same period were selected into group C. Adverse pregnancy outcomes and intrauterine infection rates were compared among three groups. Results Cases in group B had higher incidence rates of abortion,premature delivery,premature rupture of membrane,puerperal infection,neonatal asphyxia,and neonatal infection than group A and C,the differences were statistically significant（ P〈0. 05）. Conclusion BV in pregnancy period may lead to adverse pregnancy outcomes,the intrauterine infection rate and incidence of adverse pregnancy outcomes can be reduced after treatment.