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Association of Skipping Breakfast With Cardiovascular and All-Cause Mortality
Authors:Shuang Rong  Linda G. Snetselaar  Guifeng Xu  Yangbo Sun  Buyun Liu  Robert B. Wallace  Wei Bao
Affiliation:1. Department of Nutrition and Food Hygiene, School of Public Health, Medical College, Wuhan University of Science and Technology, Wuhan, China;2. Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa;3. Obesity Research and Education Initiative, University of Iowa, Iowa City, Iowa;4. Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa
Abstract:

Background

Skipping breakfast is common among U.S. adults. Limited evidence suggests that skipping breakfast is associated with atherosclerosis and cardiovascular disease.

Objectives

The authors sought to examine the association of skipping breakfast with cardiovascular and all-cause mortality.

Methods

This is a prospective cohort study of a nationally representative sample of 6,550 adults 40 to 75 years of age who participated in the National Health and Nutrition Examination Survey III 1988 to 1994. Frequency of breakfast eating was reported during an in-house interview. Death and underlying causes of death were ascertained by linkage to death records through December 31, 2011. The associations between breakfast consumption frequency and cardiovascular and all-cause mortality were investigated by using weighted Cox proportional hazards regression models.

Results

Among the 6,550 participants (mean age 53.2 years; 48.0% male) in this study, 5.1% never consumed breakfast, 10.9% rarely consumed breakfast, 25.0% consumed breakfast some days, and 59.0% consumed breakfast every day. During 112,148 person-years of follow-up, 2,318 deaths occurred including 619 deaths from cardiovascular disease. After adjustment for age, sex, race/ethnicity, socioeconomic status, dietary and lifestyle factors, body mass index, and cardiovascular risk factors, participants who never consumed breakfast compared with those consuming breakfast everyday had hazard ratios of 1.87 (95% confidence interval: 1.14 to 3.04) for cardiovascular mortality and 1.19 (95% confidence interval: 0.99 to 1.42) for all-cause mortality.

Conclusions

In a nationally representative cohort with 17 to 23 years of follow-up, skipping breakfast was associated with a significantly increased risk of mortality from cardiovascular disease. Our study supports the benefits of eating breakfast in promoting cardiovascular health.
Keywords:all-cause mortality  cardiovascular mortality  skipping breakfast  BMI  body mass index  CDC  Centers for Disease Control and Prevention  CI  confidence interval  CVD  cardiovascular disease  HEI–2010  Healthy Eating Index–2010  HR  hazard ratio  ICD  International Statistical Classification of Diseases  NCHS  National Center for Health Statistics  NDI  National Death Index  NHANES  National Health and Nutrition Examination Survey
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